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Clinical and Molecular Allergy

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  1. Content type: Research

    Allergic diseases are on the rise in many parts of the world, including the Asia–Pacific (APAC) region. Second-generation antihistamines are the first-line treatment option in the management of allergic rhinit...

    Authors: Marysia Tiongco Recto, Ma. Teresita Gabriel, Kanokvalai Kulthanan, Pongsakorn Tantilipikorn, Derrick Chen-Wee Aw, Tak Hong Lee, Ch’ng Chin Chwen, Somasundran Mutusamy, Nguyen Trong Hao, Vo Thanh Quang and Giorgio Walter Canonica

    Citation: Clinical and Molecular Allergy 2017 15:19

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  2. Content type: Research

    IgE sensitization to storage proteins from nuts and seed is often related to severe allergic symptoms. There is a risk of immunological IgE cross-reactivity between storage proteins from different species. The...

    Authors: Jenny van Odijk, Sigrid Sjölander, Peter Brostedt, Magnus P. Borres and Hillevi Englund

    Citation: Clinical and Molecular Allergy 2017 15:18

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  3. Content type: Review

    Asthma, allergic rhinitis (AR) and atopic dermatitis are very common in young people, but in the latest decades it was increasingly recognized that also individuals of higher ages, including the population ove...

    Authors: Erminia Ridolo, Anti Rogkakou, Maria Teresa Ventura, Irene Martignago, Cristoforo Incorvaia, Gabriele Di Lorenzo and Giovanni Passalacqua

    Citation: Clinical and Molecular Allergy 2017 15:17

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  4. Content type: Review

    Anticonvulsant hypersensitivity syndrome represents a rare but potentially fatal kind of adverse drug reaction. This clinical picture often hampers the flexibility with which alternative anticonvulsants or eve...

    Authors: Fabrizio De Luca, Laura Michelina Losappio, Corrado Mirone, Jan Walter Schroeder, Antonella Citterio, Maria Gloria Aversano, Joseph Scibilia and Elide Anna Pastorello

    Citation: Clinical and Molecular Allergy 2017 15:16

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  5. Content type: Research

    Sublingual immunotherapy (SLIT) is a feasible option to classical subcutaneous immunotherapy to treat respiratory allergy and is increasingly prescribed in Europe. However, the lack of reimbursement may limit ...

    Authors: Ilaria Massaro, Oliviero Rossi, Cristoforo Incorvaia and Carlo Lombardi

    Citation: Clinical and Molecular Allergy 2017 15:15

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  6. Content type: Case Report

    Hypersensitivity is a rare adverse drug reaction (ADR) associated with anti-epileptic medications. Phenytoin is one of the commonly used drugs for treatment of epilepsy that encounters a hypersensitivity react...

    Authors: Malik Ghannam, Shaden Mansour, Aya Nabulsi and Qusay Abdoh

    Citation: Clinical and Molecular Allergy 2017 15:14

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  7. Content type: Review

    Recently, some studies demonstrated that HMGB1, as proinflammatory mediator belonging to the alarmin family, has a key role in different acute and chronic immune disorders. Asthma is a complex disease characte...

    Authors: Egidio Imbalzano, Sebastiano Quartuccio, Eleonora Di Salvo, Teresa Crea, Marco Casciaro and Sebastiano Gangemi

    Citation: Clinical and Molecular Allergy 2017 15:12

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  8. Content type: Research

    Early recognition of inflammatory markers and their relation to asthma, adverse drug reactions, allergic rhinitis, atopic dermatitis and other allergic diseases is an important goal in allergy. The vast majori...

    Authors: Gennaro Tartarisco, Alessandro Tonacci, Paola Lucia Minciullo, Lucia Billeci, Giovanni Pioggia, Cristoforo Incorvaia and Sebastiano Gangemi

    Citation: Clinical and Molecular Allergy 2017 15:10

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  9. Content type: Review

    Hypersensitivity to para-phenylenediamine (PPD) and related compounds induced by temporary black henna tattoos has become a serious health problem worldwide. Different patterns of sensitization with various cl...

    Authors: Gianfranco Calogiuri, Elisabetta Di Leo, Lavjay Butani, Stefano Pizzimenti, Cristoforo Incorvaia, Luigi Macchia and Eustachio Nettis

    Citation: Clinical and Molecular Allergy 2017 15:8

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  10. Content type: Commentary

    Even if severe asthma (SA) accounts for 5–10% of all cases of the disease, it is currently a crucial unmet need, owing its difficult clinical management and its high social costs. For this reason several netwo...

    Authors: G. Senna, M. Guerriero, P. L. Paggiaro, F. Blasi, M. Caminati, E. Heffler, M. Latorre and G. W. Canonica

    Citation: Clinical and Molecular Allergy 2017 15:9

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  11. Content type: Research

    Allergen-specific immunotherapy (AIT) is the only treatment able to change the natural course of allergic diseases. We aimed at investigating the clinical efficacy of SLITOR (Serbian registered vaccine for sub...

    Authors: I. Djuric-Filipovic, Marco Caminati, D. Filipovic, C. Salvottini and Z. Zivkovic

    Citation: Clinical and Molecular Allergy 2017 15:7

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  12. Content type: Review

    Allergic rhinitis has a very high burden regarding both direct and indirect costs. This makes essential in the management of AR to reduce the clinical severity of the disease and thus to lessen its costs. This...

    Authors: Carlo Lombardi, Valerie Melli, Cristoforo Incorvaia and Erminia Ridolo

    Citation: Clinical and Molecular Allergy 2017 15:5

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  13. Content type: Review

    Hypersensitivity pneumonitis (HP), also called extrinsic allergic alveolitis, is a respiratory syndrome involving the lung parenchyma and specifically the alveoli, terminal bronchioli, and alveolar interstitiu...

    Authors: Gian Galeazzo Riario Sforza and Androula Marinou

    Citation: Clinical and Molecular Allergy 2017 15:6

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  14. Content type: Research

    Multiple sensitizations in early age have been reported to be a risk for development of asthma. This study evaluates the emergence and evolution of IgE to aeroallergens among a cohort of children with physicia...

    Authors: Mizuho Nagao, Magnus P. Borres, Mayumi Sugimoto, Carl Johan Petersson, Satoshi Nakayama, Yu Kuwabara, Sawako Masuda, Patrik Dykiel and Takao Fujisawa

    Citation: Clinical and Molecular Allergy 2017 15:4

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  15. Content type: Case Report

    Bronchial asthma is a heterogeneous respiratory condition which can be mimicked by a wide range of pathologies including upper airways stenosis. The accurate diagnosis of asthma, as with other conditions, may ...

    Authors: Fabiano Di Marco, Giuseppe Francesco Sferrazza Papa, Dejan Radovanovic and Pierachille Santus

    Citation: Clinical and Molecular Allergy 2017 15:3

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  16. Content type: Review

    Life expectancy and the number of elderly people are progressively increasing around the world. Together with other pathologies, allergic diseases also show an increasing incidence in geriatric age. This is pa...

    Authors: Maria Teresa Ventura, Nicola Scichilone, Roberto Paganelli, Paola Lucia Minciullo, Vincenzo Patella, Matteo Bonini, Giovanni Passalacqua, Carlo Lombardi, Livio Simioni, Erminia Ridolo, Stefano R. Del Giacco, Sebastiano Gangemi and Giorgio Walter Canonica

    Citation: Clinical and Molecular Allergy 2017 15:2

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  17. Content type: Research

    Sublingual immunotherapy has been proven as a well-tolerated and effective treatment for allergic rhinitis. Within this type of treatment, GRAZAX® is the most documented product in terms of safety and efficacy. T...

    Authors: Tomás Chivato, Pedro Álvarez-Calderón, Carmen Panizo, Ricardo Abengozar, César Alías, Ali Al-Baech, José Arias-Irigoyen, M. José Caballero, Lluis Conill, Silvia de Miguel, Rafael Laguna, Joan Martínez-Benazet, Francisco Matoses, Jose Camilo Martínez-Alonso, Lourdes Mendizábal, Celsa Pérez-Carral…

    Citation: Clinical and Molecular Allergy 2017 15:1

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  18. Content type: Review

    The tapeworm Taenia (T.) solium can be responsible for two different conditions: taeniasis and cysticercosis. Helminth infections in human host cause an immune response associated with elevated levels of IgE, tis...

    Authors: Paola Lucia Minciullo, Antonio Cascio, Stefania Isola and Sebastiano Gangemi

    Citation: Clinical and Molecular Allergy 2016 14:18

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  19. Content type: Review

    Eosinophilic diseases of the gastrointestinal tract, including eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE), are rare chronic pathologies of the digestive system, with an immuno-mediat...

    Authors: Erminia Ridolo, Valerie Melli, Gianluigi De’ Angelis and Irene Martignago

    Citation: Clinical and Molecular Allergy 2016 14:17

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  20. Content type: Research

    CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that ch...

    Authors: Manuela Capone, Laura Maggi, Veronica Santarlasci, Maria Caterina Rossi, Alessio Mazzoni, Gianni Montaini, Rolando Cimaz, Matteo Ramazzotti, Marie Pierre Piccinni, Giusi Barra, Raffaele De Palma, Francesco Liotta, Enrico Maggi, Sergio Romagnani, Francesco Annunziato and Lorenzo Cosmi

    Citation: Clinical and Molecular Allergy 2016 14:16

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  21. Content type: Research

    The Nef protein can be detected in plasma of HIV-1-infected patients and plays a role in the pathogenesis of HIV-1. Nef produced during the early stages of infection is fundamental in creating the ideal enviro...

    Authors: Francesca Wanda Rossi, Nella Prevete, Felice Rivellese, Antonio Lobasso, Filomena Napolitano, Francescopaolo Granata, Carmine Selleri and Amato de Paulis

    Citation: Clinical and Molecular Allergy 2016 14:15

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