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  1. Content type: Research

    Sublingual immunotherapy (SLIT) is effective, tolerable, and convenient for many allergic patients. Still, real-world evidence is scarce and the aim of this study is to assess the patient reported outcome of t...

    Authors: Christer Janson, Fredrik Sundbom, Peter Arvidsson and Mary Kämpe

    Citation: Clinical and Molecular Allergy 2018 16:14

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  2. Content type: Correspondence

    Allergic asthma is an inflammatory disorder of the airways that results from inappropriate production of IgE against harmless, environmental antigens. Sequestration of free IgE using humanized IgG anti-IgE is ...

    Authors: Sonali J. Bracken, Alexander J. Adami, Ektor Rafti, Craig M. Schramm and Adam P. Matson

    Citation: Clinical and Molecular Allergy 2018 16:13

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  3. Content type: Research

    Based on meta-analyses results, it is currently acknowledged that there is an increased risk of pneumonia in patients with chronic obstructive pulmonary disease (COPD) undergoing inhaled corticosteroids (ICS) ...

    Authors: Erminia Ridolo, Cristoforo Incorvaia, Irene Martignago, Laura Pessina, Fulvio Lauretani, Luciano Loperfido, Gian Galeazzo Riario-Sforza, Annalisa Broglia, Bruna L. Gritti and Lorenzo Panella

    Citation: Clinical and Molecular Allergy 2018 16:12

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  4. Content type: Review

    Micro-RNA represent a great family of small non-condign ribonucleic acid molecules; in particular microRNA-126 is an important member of this family and is expressed in many human cells such as cardiomyocytes,...

    Authors: Marco Casciaro, Eleonora Di Salvo, Teresa Brizzi, Carmelo Rodolico and Sebastiano Gangemi

    Citation: Clinical and Molecular Allergy 2018 16:11

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  5. Content type: Research

    Hymenoptera sting reactions are among life-threatening causes of allergy. Several epidemiology studies have assessed the risk of these kind of reactions, among the general population, around 3% of adults. This...

    Authors: Luisa Ricciardi, Francesco Papia, Giuseppe Cataldo, Mario Giorgianni, Giovanna Spatari and Sebastiano Gangemi

    Citation: Clinical and Molecular Allergy 2018 16:8

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  6. Content type: Case report

    Parasite infections stimulate total and specific IgE production that, in the case of Toxocara canis infection, corresponds to chronic allergic symptoms. There may also be other infections which have similar sympt...

    Authors: Rosanna Qualizza, Laura M Losappio and Fabiana Furci

    Citation: Clinical and Molecular Allergy 2018 16:10

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  7. Content type: Research

    The use of drugs in the elderly is very extensive because of the frequent occurrence of chronic diseases. Adverse drug reactions (ADRs) commonly occur in geriatric patients receiving multiple therapeutic regim...

    Authors: Maria Teresa Ventura, Elisa Boni, Rosa Cecere, Rosalba Buquicchio, Gian Franco Calogiuri, Irene Martignago, Cristoforo Incorvaia and Erminia Ridolo

    Citation: Clinical and Molecular Allergy 2018 16:7

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  8. Content type: Review

    Idiopathic inflammatory myopathies represent a heterogeneous group of autoimmune diseases with systemic involvement. Even though numerous specific autoantibodies have been recognized, they have not been includ...

    Authors: Boaz Palterer, Gianfranco Vitiello, Alessia Carraresi, Maria Grazia Giudizi, Daniele Cammelli and Paola Parronchi

    Citation: Clinical and Molecular Allergy 2018 16:5

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  9. Content type: Review

    Allergen immunotherapy (AIT) is the only disease-modifying treatment approved for allergic rhinitis and allergic asthma and represents a suitable therapeutic option, especially in childhood, to modify the prog...

    Authors: Matteo Ferrando, Francesca Racca, Lorena Nascimento Girardi Madeira, Enrico Heffler, Giovanni Passalacqua, Francesca Puggioni, Niccolò Stomeo and Giorgio Walter Canonica

    Citation: Clinical and Molecular Allergy 2018 16:6

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  10. Content type: Research

    Allergic Rhinitis (AR) is a high-prevalence disease. In Europe about 25% of the general population is affected, and in Italy the prevalence is estimated to be 19.8%. The Allergic Rhinitis and its Impact on Ast...

    Authors: Federica Gani, Carlo Lombardi, Laura Barrocu, Massimo Landi, Erminia Ridolo, Massimo Bugiani, Giovanni Rolla, Gianenrico Senna and Giovanni Passalacqua

    Citation: Clinical and Molecular Allergy 2018 16:4

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  11. Content type: Research

    The query “are there animals at home?” is usually administered for collecting information on anamnesis. This modality to consider exposure to pet allergens constitutes a potential bias in epidemiological studi...

    Authors: G. Liccardi, L. Calzetta, G. Baldi, A. Berra, L. Billeri, M. Caminati, P. Capano, E. Carpentieri, A. Ciccarelli, M. A. Crivellaro, M. Cutajar, M. D’Amato, I. Folletti, F. Gani, D. Gargano, D. Giannattasio…

    Citation: Clinical and Molecular Allergy 2018 16:3

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  12. Content type: Research

    Hymenoptera venom immunotherapy (VIT) is a clinically effective treatment. However, little is known about its long-term clinical efficacy and biological effects. Several mechanisms have been proposed to account f...

    Authors: Marcello Albanesi, Andrea Nico, Alessandro Sinisi, Lucia Giliberti, Maria Pia Rossi, Margherita Rossini, Georgios Kourtis, Anna Simona Rucco, Filomena Loconte, Loredana Muolo, Marco Zurlo, Danilo Di Bona, Maria Filomena Caiaffa and Luigi Macchia

    Citation: Clinical and Molecular Allergy 2018 16:2

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  13. Content type: Review

    The 2017 Nobel Prize for Physiology or Medicine, awarded for the discoveries made in the past 15 years on the genetic and molecular mechanisms regulating many physiological functions, has renewed the attention...

    Authors: Roberto Paganelli, Claudia Petrarca and Mario Di Gioacchino

    Citation: Clinical and Molecular Allergy 2018 16:1

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  14. Content type: Review

    The immunosenescence is a relatively recent chapter, correlated with the linear extension of the average life began in the nineteenth century and still in progress. The most important feature of immunosenescen...

    Authors: Maria Teresa Ventura, Marco Casciaro, Sebastiano Gangemi and Rosalba Buquicchio

    Citation: Clinical and Molecular Allergy 2017 15:21

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  15. Content type: Research

    Allergic diseases are on the rise in many parts of the world, including the Asia–Pacific (APAC) region. Second-generation antihistamines are the first-line treatment option in the management of allergic rhinit...

    Authors: Marysia Tiongco Recto, Ma. Teresita Gabriel, Kanokvalai Kulthanan, Pongsakorn Tantilipikorn, Derrick Chen-Wee Aw, Tak Hong Lee, Ch’ng Chin Chwen, Somasundran Mutusamy, Nguyen Trong Hao, Vo Thanh Quang and Giorgio Walter Canonica

    Citation: Clinical and Molecular Allergy 2017 15:19

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  16. Content type: Research

    IgE sensitization to storage proteins from nuts and seed is often related to severe allergic symptoms. There is a risk of immunological IgE cross-reactivity between storage proteins from different species. The...

    Authors: Jenny van Odijk, Sigrid Sjölander, Peter Brostedt, Magnus P. Borres and Hillevi Englund

    Citation: Clinical and Molecular Allergy 2017 15:18

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  17. Content type: Review

    Asthma, allergic rhinitis (AR) and atopic dermatitis are very common in young people, but in the latest decades it was increasingly recognized that also individuals of higher ages, including the population ove...

    Authors: Erminia Ridolo, Anti Rogkakou, Maria Teresa Ventura, Irene Martignago, Cristoforo Incorvaia, Gabriele Di Lorenzo and Giovanni Passalacqua

    Citation: Clinical and Molecular Allergy 2017 15:17

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  18. Content type: Review

    Anticonvulsant hypersensitivity syndrome represents a rare but potentially fatal kind of adverse drug reaction. This clinical picture often hampers the flexibility with which alternative anticonvulsants or eve...

    Authors: Fabrizio De Luca, Laura Michelina Losappio, Corrado Mirone, Jan Walter Schroeder, Antonella Citterio, Maria Gloria Aversano, Joseph Scibilia and Elide Anna Pastorello

    Citation: Clinical and Molecular Allergy 2017 15:16

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  19. Content type: Research

    Sublingual immunotherapy (SLIT) is a feasible option to classical subcutaneous immunotherapy to treat respiratory allergy and is increasingly prescribed in Europe. However, the lack of reimbursement may limit ...

    Authors: Ilaria Massaro, Oliviero Rossi, Cristoforo Incorvaia and Carlo Lombardi

    Citation: Clinical and Molecular Allergy 2017 15:15

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  20. Content type: Case Report

    Hypersensitivity is a rare adverse drug reaction (ADR) associated with anti-epileptic medications. Phenytoin is one of the commonly used drugs for treatment of epilepsy that encounters a hypersensitivity react...

    Authors: Malik Ghannam, Shaden Mansour, Aya Nabulsi and Qusay Abdoh

    Citation: Clinical and Molecular Allergy 2017 15:14

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