Serum interleukin-6 level and its association with pulmonary involvement in progressive systemic sclerosis; a case-control study

Table 2 The mean serum level of IL-6 (pg/mL) in terms of sex, age and disease duration in both groups of the study

Parameters	Group	Frequency	Mean ± Standard deviation	P-value^a
Sex
Male	Case	8	141.7 ± 103.2	0.007
Male	Control	12	14.3 ± 19.3	0.007
Female	Case	22	48.1 ± 81.2	0.693
Female	Control	18	68.2 ± 102.2	0.693
Active	Case	21	79.9 ± 94.3	0.414
Active	Control	6	51.1 ± 88.1	0.414
Inactive	Case	9	57.1 ± 101.8	0.793
Inactive	Control	24	45.6 ± 84.4	0.793
Age
< 50 years	Case	13	32.7 ± 59.1	0.987
< 50 years	Control	23	55.5 ± 93.3	0.987
≥ 50 years	Case	17	103.9 ± 107.5	0.057
≥ 50 years	Control	7	17.6 ± 23.9	0.057
Disease duration
< 10 years	Case	9	103.9 ± 110.0	0.140
< 10 years	Control	24	51.4 ± 92.6	0.140
≥ 10 years	Case	21	59.8 ± 88.0	0.770
≥ 10 years	Control	6	27.6 ± 22.2	0.770

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