Prescription rate and treatment patterns for allergic rhinitis from 2010 to 2018 in South Korea: a retrospective study

Table 1 Rates of prescription and pattern by year

Year	2010	2011	2012	2013	2014	2015	2016	2017	2018	Beta	P-value
Antihistamines
Total antihistamines	84.47	84.44	84.05	83.87	81.81	80.77	80.70	80.53	79.75	-0.67	< 0.001
First generation	29.13	29.25	29.12	28.78	27.27	26.25	25.70	24.56	23.41	-0.77	< 0.001
Second generation	73.56	73.89	73.78	73.97	72.20	71.77	72.20	72.46	72.02	-0.26	0.010
Steroids
Total steroids	30.43	32.17	32.09	33.38	32.90	33.69	35.28	38.17	38.50	0.95	< 0.001
Nasal steroids	9.70	10.51	10.01	10.54	10.09	10.07	11.90	15.08	14.67	0.61	0.008
Systemic steroids	23.60	25.04	25.25	26.24	26.12	26.94	27.36	28.21	28.70	0.58	< 0.001
Other drugs
Leukotriene antagonists	11.13	12.88	17.58	19.86	21.85	22.98	21.08	19.91	26.56	1.55	0.002
Systemic decongestants	51.97	53.05	52.37	52.46	54.91	55.32	56.36	57.13	56.34	0.68	< 0.001
Cough and cold preparations	58.79	56.71	56.43	55.99	57.23	56.77	57.36	57.31	58.17	0.03	0.791
Prescription combination pattern
First-generation antihistamines only	10.50	10.08	9.83	9.43	9.19	8.60	8.12	7.59	7.28	-0.41	< 0.001
Second-generation antihistamines only	49.46	48.96	49.04	48.86	48.53	48.52	47.71	46.57	47.14	-0.32	< 0.001
Antihistamines and nasal steroids	7.99	8.74	8.28	8.72	8.32	8.28	9.83	12.50	12.09	0.51	0.009
Nasal steroids only	1.71	1.77	1.73	1.82	1.77	1.79	2.06	2.58	2.58	0.11	0.004
First-choice prescription
Antihistamines only	76.33	75.76	75.27	74.68	72.35	71.1	70.06	68.04	67.27	-1.22	< 0.001
Nasal steroids only	1.94	1.99	1.93	2.06	1.95	1.96	2.21	2.92	2.90	0.12	0.011
Antihistamines and nasal steroids	4.72	5.15	4.88	5.22	4.97	4.94	5.69	7.42	7.24	0.30	0.008

Prescription and pattern rates per 100 patients are presented by year. Rates were sex- and age-standardized according to the population composition of 2010

ISSN: 1476-7961