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Table 3 Peanut extract and allergen-specific IgE in challenge confirmed peanut allergic and peanut tolerant children

From: Peanut components measured by ISAC: comparison with ImmunoCap and clinical relevance in peanut allergic children

FEIA

Peanut tolerant (N = 45)

Peanut allergic (N = 65)

P value

N (%)

Median (range)

N (%)

Median (range)

Peanut extract

34 (76)

1.7 (0–76.50)

63 (97)

8.1 (2.79 to > 100)

< 0.01

 

Peanut tolerant (N = 49)

Peanut allergic (N = 64)

P value

N (%)

Median (range)

N (%)

Median (range)

Ara h 2

13 (27)

0.09 (0–4.40)

59 (92)

3.05 (0.03–462)

< 0.01

ISAC

Peanut tolerant (N = 51)

Peanut allergic (N = 66)

P value

N (%)

Median (range)

N (%)

Median (range)

Ara h 1

5 (10)

0.00 (0–2.80)

32 (49)

0.00 (0–67.49)

< 0.01

Ara h 2

14 (27)

0.00 (0–7.43)

62 (94)

3.71 (0–180)

< 0.01

Ara h 3

3 (6)

0.00 (0–0.69)

18 (27)

0.00 (0–12.49)

< 0.01

Ara h 6

14 (27)

0.00 (0–8.13)

61 (92)

3.64 (0–102.39)

< 0.01

Ara h 8

21 (41)

0.00 (0–136.61)

25 (38)

0.00 (0–23.89)

NS

Ara h 9

4 (8)

0.00 (0–8.62)

4 (6)

0.00 (0–2.69)

NS

Storage proteins

 None

30 (59)

 

2 (3)

 

< 0.01

 1

10 (20)

 

4 (6)

 

0.03

  ≥ 2

11 (22)

 

60 (91)

 

< 0.01

  1. Values are presented as number of positive (%) and median (ranges). Chi square and Mann Whitney U tests were performed