The blocking effect of the glycoprotein IIb/IIIa receptor in the mouse model of asthma

Table 1 Comparisons between therapeutic effects of tirofiban and clopidogrel in asthma

	OVA (%)	Tirofiban 5 mg/kg (%)	Clopidogrel 10 mg/kg (%)	P value
Airway hyperresponsiveness	100	88.54	82.78	0.999
Total cell count in BAL	100	42.45	15.77	0.701
Eosinophil count in BAL	100	34.82	15.07	0.848
IL-4	100	49.85	35.56	0.885
IL-5	100	85.10	50.11	0.893
IL-13	100	38.21	10.40	0.657
PF4	100	39.08	18.65	0.562
ECP	100	44.29	24.90	0.736
Platelet-eosinophil aggregation	100	65.70	53.81	0.779

Data are expressed decreased as percentages when the results of OVA mice are designated as 100 %. P values were calculated for the comparisons between the tirofiban and clopidogrel groups
AHR airway hyperresponsiveness, BAL bronchoalveolar lavage, PF4 platelet factor 4, ECP eosinophilic cationic protein

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