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Table 1 Grading of the severity of immediate hypersensitivity reactions to CM [16]

From: SIRM-SIAAIC consensus, an Italian document on management of patients at risk of hypersensitivity reactions to contrast media

Symptoms
Grade Skin   Abdomen Respiratory tract Circulation
I Pruritus
Flush
Urticaria
Angioedema
    
II Pruritus
Flush
Urticaria
Angioedema
(Not obligatory) Nausea
Cramping
Rhinorrhea
Hoarseness
Dyspnea
Tachycardia (δ > 20/min)
III Pruritus
Flush
Urticaria
Angioedema
(Not obligatory) Vomiting
Defecation
Diarrhea
Laryngeal edema
Bronchospasm
Cyanosis
Hypotension (δ > 20 mmHg syst.)
Arrhythmia
Shock
IV Pruritus
Flush
Urticaria
Angioedema
(Not obligatory) Vomiting
Defecation
Diarrhea
Respiratory arrest Circulatory arrest