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Table 2 Patient characteristics and inflammation markers in relation to allergen component sensitization (n = 408)

From: Sensitization to storage proteins in peanut and hazelnut is associated with higher levels of inflammatory markers in asthma

 Peanut and Hazelnut in any combination
PH:1 PH:2 PH:3
Peanut
P:1 P:2 P:3
Hazelnut
H:1 H:2 H:3
Number (%)179 (44)156 (38)73 (18)207 (51)141 (34)60 (15)188 (46)179 (44)41 (10)
Age (years)a20.9 ± 0.521.2 ± 0.617.6 ± 0.7*,#21 ± 0.521 ± 0.617.2 ± 0.7¤,#20.8 ± 0.520.5 ± 0.517.9 ± 0.9
Femaleb95 (53)83 (53)30 (41)107 (52)77 (55)24 (40)101 (54)90 (50)17 (41)
FeNO (ppb)312.7 (11.3–14.2)16.7 (14.8–18.7)*23.2 (19.6–27.5)*,#13.1 (11.7–14.5)17.3 (15.4–19.5)¤23.6 (19.5–28.5)¤,#12.8 (11.5–14.3)17.7 (15.8–19.9)23.5 (19.1–29)
FEV1 (%)192.9 ± 1.192.2 ± 1.289.6 ± 1.693 ± 191.8 ± 1.289.4 ± 1.892.9 ± 191.9 ± 189 ± 2.4
Methacholine ch.test (PD20)d0.4 (0.1–3)0.3 (0.1–1.8)0.1 (0.1–0.4)*0.4 (0.1–2.9)0.3 (0.1–1.2)0.1 (0–0.1)0.4 (0.1–7.2)0.3 (0.1–1.2)0.1 (0–0.6)
Eosinophils (109/L)c0.15 (0.13–0.16)0.17 (0.15–0.2)0.34 (0.29–0.41)*,#0.14 (0.13–0.16)0.19 (0.17–0.22)¤0.34 (0.28–0.41)¤,#0.15 (0.13–0.17)0.19 (0.17–0.22)0.37 (0.29–0.46)∆,☼
ECP (µg/L)c11.6 (10.5–12.7)12.4 (11.1–13.8)20 (17–23.5)*,#11.6 (10.6–12.7)13.2 (11.7 –14.9)19.7 (16.5–23.5)¤,#11.7 (10.6–12.8)13.1 (11.8–14.5)22.1 (17.8–27.4)∆,☼
Total IgE (kU/L)c58 (46–73)213 (176–258)*523 (396–689)*,#63 (51–78)265 (216–325)¤515 (378–701)¤,#62 (49–77)226 (190–270)803 (557–1158)∆,☼
Eczema (ever)b67 (37)100 (64)*59 (81)*,#77 (37)101 (72)¤48 (80)¤73 (39)118 (66)35 (85)∆,☼
Inh.corticosteroids (µg/day)c404 (369–443)416 (375–461)358 (315–407)400 (369–434)425 (380–475)345 (299–399)404 (370–442)404 (367–444)368 (307–442)
Birch pollen sensitizationb13 (7)151 (97) *64 (88)*,#39 (19)137 (97) ¤52 (87)¤,#14 (7)176 (98)38 (93)
Ara h 8 sensitizationb   132 (94)42 (70)#   
Cor a 1 sensitizationb      169 (94)35 (85)
  1. PH:1 not sensitized to peanut or hazelnut; PH::2 sensitized to peanut and/or Ara h8 and/or hazelnut and/or Cor a 1 but not to any of Ara h 1, 2, 3, Cor a 9, 14; PH::3 sensitized to peanut and/or Ara h8 and/or hazelnut and/or Cor a and to any of Ara h 1, 2, 3, Cor a 9, 14
  2. P:1 not sensitized to peanut; P:2 sensitized to peanut but not to any of Ara h 1, 2, 3; P:3 sensitized to peanut and to any of Ara h 1, 2, 3
  3. H:1 not sensitized to hazelnut; H:2 sensitized to hazelnut but not to any of Cor a 9, 14; H:3 sensitized to hazelnut and to any of Cor a 9, 14
  4. aMean ± SD, bNumber (percentage), cGeometric Mean (95% CI), dmedian (IQR)
  5. * p < 0.05 compared to group A1
  6. #p < 0.05 compared to group A2
  7. ¤p < 0.05 compared to group B1
  8. ##p < 0.05 compared to group B2
  9. p < 0.05 compared to group C1
  10. p < 0.05 compared to group C2