Skip to main content

Table 1 Comparison between the laboratory findings in the two MDA5+ patients with dermatomyositis

From: MDA5-positive dermatomyositis: an uncommon entity in Europe with variable clinical presentations

 

Patient #1

Patient #2

Reference values

Total blood counts

 WBC

1.67

5.17

4–10 × 109/L

 Neutrophils

1.08

1.66

1.5–7.5 × 109/L

 Lymphocytes

0.27

2.67

1–5 × 109/L

 Hb

9.8

12.8

13–16 g/dL

 PLTs

130

217

140–440 × 109/L

Liver enzymes

 AST

244

28

15–37 U/L

 ALT

263

48

12–65 U/L

Cholestasis indexes

 ɣ-GT

399

117

5–85 U/L

 AP

120

92

50–136 U/L

Total bilirubin

0.7

0.5

0.2–1 mg/dL

Muscle enzymes

 LDH

483

255

84–246 U/L

 CPK

662

28

35–232 U/L

 Aldolase

11.2

7.4

<7.3 U/mL

Indexes of inflammation

 ESR

50

41

2–10 mm/h

 CRP

<9

<9

<9 mg/L

 Ferritin

4218

292

26–388 ng/mL

Autoantibodies

 ANA

1/640

Neg

<1/80

 Anti-MDA5

+++ (72)

+++ (58)

Neg

 Anti-Ro52

+++ (84)

Neg

Neg

  1. All the values reported were measured at admission in the absence of therapy. Anti-nuclear antibodies (ANA) were determined by means of indirect immunofluorescence on Hep2 cells (Euroimmun). Anti-MDA5 and anti-Ro52 kDa were determined by a validated commercial Immunoblot method (Euroimmun) (in brackets, levels of autoantibodies as automatically calculated by the EUROLineScan software)
Back to article page

Clinical and Molecular Allergy

ISSN: 1476-7961

Contact us