Table 4 A summary of treatment options for Henoch-Schonlein Purpura
From: The clinical implications of adult-onset henoch-schonelin purpura
Medication | Indication |
|---|---|
Acetaminophen, NSAID | Mild eruption, arthritis |
Colchicine | Severe or recurrent skin disease |
Oral glucocorticoids | Severe eruption, cutaneous edema, severe colicky abdominal pain, scrotal and testicular involvement |
Parenteral glucocorticoids | Same as oral; unable to tolerate oral medications |
High dose parenteral pulse glucocorticoid | Nephrotic range proteinuria |
High dose IV pulse glucocorticoids combined with other forms of immunosuppression (such as cyclophosphamide) | Rapidly progressive glomerulonephritis Hemorrhagic involvement of lungs or brain |
Plasmapheresis and/or IGIV | Refractory to combination therapy Massive hemorrhage in gastrointestinal or other organs |