Evaluation for Wiskott-Aldrich syndrome (WAS) and related allelic variant, X-linked thrombocytopenia (XLT). A) Pedigree analysis for patient (Case 2) with X-linked thrombocytopenia (XLT). B) Flow cytometric analysis for Wiskott-Aldrich syndrome protein (WASP) in lymphocytes in XLT patient and carrier. Figure reproduced with permission of American Society of Hematology, from "X-linked thrombocytopenia identified by flow cytometric demonstration of defective Wiskott-Aldrich syndrome protein in lymphocytes", Kanegane et al, 95: 1110-1111, 2000; permission conveyed through Copyright Clearance Center, Inc . C) Flow cytometric analysis for Wiskott-Aldrich syndrome protein (WASP) in lymphocytes in WAS patient. Figure reprinted from Journal of Immunological Methods, 260, Kawai et al., Flow cytometric determination of intracytoplasmic Wiskott-Aldrich syndrome protein in peripheral blood lymphocyte subpopulations, p.195-205 , Copyright (2000), with permission from Elsevier.