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Table 3 EPO release from neutrophils spontaneously and after C3b-stimulation (at 0 and 20 min) in allergic rhinitis and allergic asthma during pollen season and after nasal and bronchial challenge.

From: Patients with allergic rhinitis and allergic asthma share the same pattern of eosinophil and neutrophil degranulation after allergen challenge

  Spontanous degranulation of EPO Stimulated degranulation of EPO p-value p-value
  0 min 20 min 0 min 20 min   
Pollen season       
Rhinitics 0.42 0.37 0.45 2.05 0.18 0.02*
  (0.12 - 0.63) (0.13 - 0.61) (0.35 - 0.92) (1.08 - 3.0)   
Asthmatics 0.32 0.30 0.39 1.58 - 0.59 0.11
  (0.17 - 0.52) (0.08 - 0.43) (0.38 - 0.74) (1.52 - 3.46)   
Nasal challenge       
Rhinitics 0.50 0.49 0.61 1.4 0.9 0.07
  (0.38 - 0.62) (0.36 - 0.62) (0.51 - 0.71) (1.2 - 1.6)   
Asthmatics 0.49 0.44 0.54 1.86 0.07 0.07
  (0.45 - 0.69) (0.42 - 0.46) (0.48 - 0.74) (1.54 - 3.22)   
Bronchial challenge       
Rhinitics 0.28 0.32 0.55 1.99 0.7 0.04*
  (0.21 - 0.46) (0.16 - 0.40) (0.26 - 0.93) (1.71 - 2.17)   
Astmatics 0.44 0.41 0.52 1.84 0.14 0.07
  (0.31 - 0.62) (0.26 - 0.56) (0.35 - 0.64) (1.04 - 2.04)   
  1. * Release of EPO in % of total cell content