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Table 3 EPO release from neutrophils spontaneously and after C3b-stimulation (at 0 and 20 min) in allergic rhinitis and allergic asthma during pollen season and after nasal and bronchial challenge.

From: Patients with allergic rhinitis and allergic asthma share the same pattern of eosinophil and neutrophil degranulation after allergen challenge

 

Spontanous degranulation of EPO

Stimulated degranulation of EPO

p-value

p-value

 

0 min

20 min

0 min

20 min

  

Pollen season

      

Rhinitics

0.42

0.37

0.45

2.05

0.18

0.02*

 

(0.12 - 0.63)

(0.13 - 0.61)

(0.35 - 0.92)

(1.08 - 3.0)

  

Asthmatics

0.32

0.30

0.39

1.58 -

0.59

0.11

 

(0.17 - 0.52)

(0.08 - 0.43)

(0.38 - 0.74)

(1.52 - 3.46)

  

Nasal challenge

      

Rhinitics

0.50

0.49

0.61

1.4

0.9

0.07

 

(0.38 - 0.62)

(0.36 - 0.62)

(0.51 - 0.71)

(1.2 - 1.6)

  

Asthmatics

0.49

0.44

0.54

1.86

0.07

0.07

 

(0.45 - 0.69)

(0.42 - 0.46)

(0.48 - 0.74)

(1.54 - 3.22)

  

Bronchial challenge

      

Rhinitics

0.28

0.32

0.55

1.99

0.7

0.04*

 

(0.21 - 0.46)

(0.16 - 0.40)

(0.26 - 0.93)

(1.71 - 2.17)

  

Astmatics

0.44

0.41

0.52

1.84

0.14

0.07

 

(0.31 - 0.62)

(0.26 - 0.56)

(0.35 - 0.64)

(1.04 - 2.04)

  
  1. * Release of EPO in % of total cell content