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Table 1 Demographic data of the control group and patients with allergic rhinitis and allergic asthma (mean and range).

From: Patients with allergic rhinitis and allergic asthma share the same pattern of eosinophil and neutrophil degranulation after allergen challenge

 

Control group

Allergic rhinitis

Allergic asthma

p-value

 

n = 5

(n = 9)

(n = 8)

(AR/AA)***

Gender (male/female)

2/3

8/1

3/8

0.36

Age

38 (27-58)

43 (24 - 66)

41 (19 - 56)

0.85

Ex-smoker (>10 yr)

0

2

1

0.79

SPT birch (in mm2)

0

47.1 (20 - 88)

43.6 (26 - 64)

1.0

IgE for birch, Class 0-5

0

3.1 (2 - 4)

3.4 (2 - 5)

0.43

FEV1 (L)

3.59(3.02-3.95)

4.0 (2.4 - 4.9)

3.5 (2.6 - 4.0)

0.12

FEV 1 % of predicted

105 (88-125)

102 (75 - 139)

97 (83 - 108)

0.44

PEFR (L/min)

571 (348-854)

615 (415 - 826)

504 (347 - 652)

0.18

PEFR % of predicted

117 (84-169)

113 (82 - 140)

101 (73 - 133)

0.25

FEV 1 -decrease in % *

1.1 (-0.5-6.2)

0.42 (-5.6 - 5.8)

6.81 (1.55 - 16.4)

0.02

PD 20 (birch) (SQE)**

-

34 500 (3850 - 150 000)

3 700 (2450 - 7700)

0.04

Morning PEFR (L/min) diary during pollen season

-

575 (550 - 620)

475 (433 - 551)

0.02

Evening PEFR (L/min) diary during pollen season

-

610 (555 - 630)

478 (449 - 551)

0.005

  1. * After inhalation of hypertonic 4.5% saline solution at baseline.
  2. ** After bronchial allergen challenge (median and range).
  3. *** AR = allergic rhinitis and AA = allergic asthma.