Table 2 Adjusted1) associations of 10 cytokine polymorphisms with self-reported hay fever in the ECRHS-Basel Study.
From: Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)
Genotype | Â | cases/controls2) | Odds Ratio | 95% Confidence Interval | P-value |
|---|---|---|---|---|---|
IL4 (-589C>T) | CC | 140/89 | 1 | -- | -- |
rs2243250 | CT | 47/31 | 0.99 | 0.58 – 1.68 | 0.98 |
|  | TT | 5/5 | 0.56 | 0.16 – 2.03 | 0.38 |
IL4R Q576R (A>G) | AA | 128/71 | 1 | -- | -- |
rs1801275 | AG | 58/45 | 0.68 | 0.42 – 1.13 | 0.12 |
|  | GG | 5/5 | 0.59 | 0.16 – 2.11 | 0.39 |
IL6(-174G>C) | GG | 65/33 | 1 | -- | -- |
rs1800795 | GC | 97/66 | 0.77 | 0.45 – 1.30 | 0.32 |
|  | CC | 28/25 | 0.58 | 0.29 – 1.15 | 0.12 |
IL10 (-1082G>A) | GG | 60/48 | 1 | -- | -- |
rs1800896 | GA | 96/50 | 1.58 | 0.94 – 2.6 | 0.08 |
|  | AA | 36/26 | 1.15 | 0.61 – 2.18 | 0.66 |
IL10 (-819C>T) | CC | 102/71 | 1 | -- | -- |
rs1800871 | CT | 77/42 | 1.26 | 0.77 – 2.04 | 0.35 |
|  | TT | 11/12 | 0.64 | 0.27 – 1.54 | 0.32 |
IL12p40(1188A>C) | AA | 114/74 | 1 | -- | -- |
rs3212227 | AC | 69/44 | 0.99 | 0.61 – 1.59 | 0.95 |
|  | CC | 9/6 | 1.05 | 0.36 – 3.09 | 0.93 |
IL13 R130Q (A>G) | GG | 127/82 | 1 | -- | -- |
rs20541 | GA | 57/38 | 0.96 | 0.58 – 1.58 | 0.87 |
|  | AA | 6/4 | 0.99 | 0.27 – 3.68 | 0.99 |
IL18(-137G>C) | GG | 101/55 | 1 | -- | -- |
rs187238 | GC | 73/54 | 0.75 | 0.46 – 1.22 | 0.25 |
|  | CC | 18/15 | 0.65 | 0.30 – 1.39 | 0.27 |
TNF(-308G>A) | GG | 135/84 | 1 | -- | -- |
rs1800629 | GA | 53/35 | 0.94 | 0.57 – 1.57 | 0.83 |
|  | AA | 4/4 | 0.58 | 0.14 – 2.40 | 0.45 |
CD14 (-159C>T) | CC | 49/41 | 1 | -- | -- |
rs2569190 | CT | 89/55 | 1.36 | 0.79 – 2.32 | 0.26 |
|  | TT | 51/26 | 1.64 | 0.88 – 3.09 | 0.12 |