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Figure 4 | Clinical and Molecular Allergy

Figure 4

From: The basophil activation test by flow cytometry: recent developments in clinical studies, standardization and emerging perspectives

Figure 4

Representative increased expression of CD203c after allergen challenge in a patient allergic to Dermatophagoïdes pteronyssinus (d1). Gated CRTH2-positive basophils (after excluding Th2 lymphocytes as described in figure 3) are presented on the basis of CD203c-CRTH2 staining: before stimulation (negative control, upper left dot-plot), after anti-IgE challenge (positive control, upper right) and after allergen challenge at 3 different concentrations (dose-effect response, lower dot-plots). Activated basophils: percentage of basophils expressing CD203c.

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