Remission of severe aphthous stomatitis of celiac disease with etanercept

Table 3 Systemic medications which have been used for treatment of RAU

Medication	Number of patients	Results/outcome	Reference
Pentoxifylline 400 mg TID	26 people	↓ ulcer size	[14]
	14 patients	↓ ulcers number
	12 control	↓ ulcers number
Doxycyline 20 mg BID	50 patients	↑ remission	[15]
Doxycyline 20 mg BID	50 patients	↓ pain	[15]
Zinc sulfate 150 mg BID	45 patients	↓ ulcer size	[16]
Zinc sulfate 150 mg BID	45 patients	↓ symptoms	[16]
Cholchicine (1–2) mg BID	169 patients	↓ ulcer number	[17]
Cholchicine (1–2) mg BID	169 patients	↓ disease duration	[17]
Clofazimine 100 mg QD For 1 month	23 patients	↓ ulcers number	[18]
		↓ disease duration
		In 44%
Prednisone up to 25 mg	60 patients	↓ ulcers number	[19]
Prednisone up to 25 mg	60 patients	Faster healing	[19]
Montelukast 10 mg QD	60 patients	↓ ulcers number	[20]
Montelukast 10 mg QD	60 patients	Faster healing	[20]
Thalidomide 50 mg QD 200 mg QD for HIV patients	20 HIV patients	Induce remission	[21]
Thalidomide 50 mg QD 200 mg QD for HIV patients	20 HIV patients	In HIV patients	[21]
Chlorambucil 0.1 mg/kg	Single case report	Remission	[22]
Infliximab 5 mg/kg QD	Single case report	Remission	[23]
Etanercept 25 mg BiWeekly	40 patients	↓ ulcers number	[24]
Levamisole	9 patients	↓ ulcers number	[25]

ISSN: 1476-7961