Patient | SCARs | Culprit drug | Latency (weeks) | Treatment | Tolerated anticonvulsants | Other tolerated drugs |
---|---|---|---|---|---|---|
P1 | DRESS | Phenytoin | 3 | Methylprednisolone for 3Â months | Clonazepam | Ibuprofen, clarithromycin |
P2 | DRESS | Phenytoin | 3 | Prednisone for 1Â year | Levetiracetam | Metamizole, tramadol, amoxicillin, clarithromycin, ketoprofen, metoclopramide, rituximab, lercanidipine |
P3 | SJS | Lamotrigine | 4 | Hydrocortisone bolus, prednisone for 1Â month and immunoglobulin intravenously | Delorazepam and lormetazepam | Echinocandin |
P4 | SJS | Phenytoin | 4 | Hydrocortisone bolus, prednisone for 1Â month and immunoglobulin intravenously | Diazepam | Teicoplanin, haloperidol |
P5 | TEN | Valproic acid | 2 | Prednisone for 1Â month and immunoglobulin intravenously | Diazepam and levetiracetam | Meropenem |
P6 | TEN | Lamotrigine | 2 | Prednisone for 1Â month and immunoglobulin intravenously | Diazepam and levetiracetam | Teicoplanin |