Disease | Culprit drug | HLA haplotype | Population | Authors (ref. number) |
---|
SJS ⁄TEN | Carbamazepine | HLA-B*15:02 | Asians | [11–13] |
SJS/TEN and DRESS | Carbamazepine | HLA-A*31:01 | Europeans | [14, 15] |
SJS/TEN and DRESS | Phenytoin | HLA-B*15:13 and -B*15:02 | Malaysians | [16] |
- SJS: Stevens Johnson syndrome, TEN: toxic epidermal necrolysis, DRESS: drug reaction with eosinophilia and systemic symptoms