Table 4 Immune adjuvant properties of metal nanoparticles
From: Engineered metal based nanoparticles and innate immunity
NPs | Cells | Effects | Ref |
|---|---|---|---|
AgNPs | Lung | -Reduction of IL-4, IL-5, IL-13 | [87] |
-Reduction of NF-kB | |||
-Reduction of eosinophilic inflammation (OVA-induced ) | |||
Fullerenes | Mast cells | -Inhibition of IgE dependent mediator release | [88] |
-Reduction of phosphorylation Syk | |||
-Inhibition of allergen-induced ROS | |||
AuNPs AgNPs | Mast cells | -Inhibition of degranulation and serotonine secretion | [89] |
AgNPs | Rat model of spinal cord injury | -Higher anti-NgR antibody | [90] |
AlNPs | Dendritic cells | -Increased MHC and CD86, Cd80 and CD40 (> than Al ions) | [91] |
Fe2O3NPs | Dendritic cells | -Th1 immune activation |