Table 5 Infectious Consequences of CGD
From: Chronic granulomatous disease: a review of the infectious and inflammatory complications
Type | Organ System | Manifestations | Etiology | Diagnosis |
|---|---|---|---|---|
Infectious | Â | Â | Â | Â |
| Â | Blood stream | Sepsis | B Cepacia Pseudomonas Serratia Staphylococcus Salmonella | Blood cultures Echocardiogram |
| Â | Pulmonary | Pneumonia | Aspergillus Nocardia Serratia Pseudomonas Staphylococcus Klebsiella Candida Others | Radiolology Cultures Biopsy |
| Â | Cutaneous | Impetigo Abscess | Staphylococcus Klebsiella Aspergillus/Candida Serratia | Aspirate cultures Biopsy |
| Â | Lymph node | Adenitis Adenopathy | Candida/Nocardia Aspergillus Serratia/Klebsiella | Fine needle aspirate Cultures Biopsy |
| Â | Liver | Abscess | Staphylococcus Streptococcus Aspergillus/Nocardia Serratia | Ultrasound or CT Aspirate Biopsy |
| Â | Bone | Osteomyelitis | Serratia, Aspegillus Staphylococcus Pseudomonas/Nocardia | Bone scan CT/Biopsy |
| Â | GI Tract | Perirectal abscess Fistulae | Enterobacteriaceae Staphylococcus | Biopsy Cultures |
| Â | Urinary | Pyelonephritis | Enterobacteriaceae | Cultures IVP/CT etc |
| Â | CNS | Meningitis Brain abscess | Candida, Haemophilus Aspergillus Staphylococcus | LP, cultures CT/MRI Biopsy |