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  2. The prediction of allergen cross-reactivity is currently largely based on linear sequence data, but will soon include 3D information on homology among surface exposed residues. To evaluate procedures for these...

    Authors: Rob C Aalberse
    Citation: Clinical and Molecular Allergy 2007 5:2
    Content type: Commentary Published on:

  3. There has been a worldwide increase in allergy and asthma over the last few decades, particularly in industrially developed nations. This resulted in a renewed interest to understand the pathogenesis of allerg...

    Authors: Viswanath P Kurup, Christy S Barrios, Raghavan Raju, Bryon D Johnson, Michael B Levy and Jordan N Fink
    Citation: Clinical and Molecular Allergy 2007 5:1
    Content type: Research Published on:

  4. The mechanisms for the association between birth by cesarean section and atopy and asthma are largely unknown.

    Authors: Ngoc P Ly, Begoña Ruiz-Pérez, Andrew B Onderdonk, Arthur O Tzianabos, Augusto A Litonjua, Catherine Liang, Daniel Laskey, Mary L Delaney, Andrea M DuBois, Hara Levy, Diane R Gold, Louise M Ryan, Scott T Weiss and Juan C Celedón
    Citation: Clinical and Molecular Allergy 2006 4:13
    Content type: Research Published on:

  5. Entomopathogenic fungi such as Beauveria bassiana are considered promising biological control agents for a variety of arthropod pests. Beauveria species, however, have the potential to elicit allergenic reactions...

    Authors: Greg S Westwood, Shih-Wen Huang and Nemat O Keyhani
    Citation: Clinical and Molecular Allergy 2006 4:12
    Content type: Research Published on:

  6. Aspergillus fumigatus, a widely distributed fungus, has been implicated in causing life threatening infections as well as severe asthma and allergic diseases in man. Allergic affliction like allergic bronchopulmo...

    Authors: Viswanath P Kurup, Alan P Knutsen, Richard B Moss and Naveen K Bansal
    Citation: Clinical and Molecular Allergy 2006 4:11
    Content type: Research Published on:

  7. The potato is one of the most common types of genetically modified (GM) food. However, there are no published data evaluating the impact of genetic manipulations on the allergenicity of GM potatoes. To compare...

    Authors: Soo-Keol Lee, Young-Min Ye, Sung-Ho Yoon, Bou-Oung Lee, Seung-Hyun Kim and Hae-Sim Park
    Citation: Clinical and Molecular Allergy 2006 4:10
    Content type: Research Published on:

  8. Atopy and allergic phenotypes are biologically characterized by an imbalanced T helper cell response skewed towards a type 2 (TH2) immune response associated with elevated serum immunoglobulin E (IgE) levels. ...

    Authors: M Imboden, A Nieters, AJ Bircher, M Brutsche, N Becker, M Wjst, U Ackermann-Liebrich, W Berger and NM Probst-Hensch
    Citation: Clinical and Molecular Allergy 2006 4:9
    Content type: Research Published on:

  9. In spite of recent advances with experiments on animal models, strongyloidiasis, an infection caused by the nematode parasite Strongyloides stercoralis, has still been an elusive disease. Though endemic in some d...

    Authors: Raja S Vadlamudi, David S Chi and Guha Krishnaswamy
    Citation: Clinical and Molecular Allergy 2006 4:8
    Content type: Review Published on:

  11. Chemokine receptors have been suggested to be preferentially expressed on CD4+ T cells with CCR3 and CCR8 linked to the T helper (Th) 2 subset and CCR5 and CXCR3 to the Th1 subset, however this remains controv...

    Authors: Mille Holse, Kristian Assing and Lars K Poulsen
    Citation: Clinical and Molecular Allergy 2006 4:6
    Content type: Research Published on:

  12. House dust mite allergens (HDM) cause bronchoconstriction in asthma patients and induce an inflammatory response in the lungs due to the release of cytokines, chemokines and additional mediators. The mechanism...

    Authors: Henk F Kauffman, Michael Tamm, J André B Timmerman and Peter Borger
    Citation: Clinical and Molecular Allergy 2006 4:5
    Content type: Research Published on:

  13. Vaccination with naked DNA encoding antigen induces cellular and humoral immunity characterized by the activation of specific Th1 cells.

    Authors: Nacksung Kim, Soon Seog Kwon, Jaechun Lee, Sohyung Kim and Tai June Yoo
    Citation: Clinical and Molecular Allergy 2006 4:4
    Content type: Research Published on:

  14. Allergic bronchopulmonary aspergillosis occurs in 7–10% of cystic fibrosis (CF) and 1–2% of asthmatic patients. HLA-DR restriction and increased sensitivity to IL-4 stimulation have been proposed as risk facto...

    Authors: Alan P Knutsen, Barbara Kariuki, Judy D Consolino and Manoj R Warrier
    Citation: Clinical and Molecular Allergy 2006 4:3
    Content type: Research Published on:

  15. Interleukin 8 (IL8) belongs to the family of chemokines. It mediates the activation and migration of neutrophils from peripheral blood into tissue and hereby plays a pivotal role in the initiation of inflammat...

    Authors: Beena Puthothu, Marcus Krueger, Jessica Heinze, Johannes Forster and Andrea Heinzmann
    Citation: Clinical and Molecular Allergy 2006 4:2
    Content type: Research Published on:

  16. Avoidance of allergens is still recommended as the first and best way to prevent allergic illnesses and their comorbid diseases. Despite a variety of attempts there has been very limited success in the area of...

    Authors: C Steven Smith, Scott A Smith, Thomas J Grier and David E Justus
    Citation: Clinical and Molecular Allergy 2006 4:1
    Content type: Research Published on:

  17. A 25-year-old, with type I Diabetes Mellitus with a previous diagnosis of Protamine Allergy but not to human Insulin, started to notice anaphylactic reactions inmmediatly after bolus with Insulin. Skin prick a...

    Authors: Victor Matheu, Eva Perez, Marta Hernández, Elisa Díaz, Ricardo Darias, Abel González, Jose C García, Inmaculada Sánchez, Laura Feliciano, Agueda Caballero and Fernando de la Torre
    Citation: Clinical and Molecular Allergy 2005 3:16
    Content type: Case Report Published on:

  18. IL4/IL4RA pathway plays an important role in atopy and asthma. Different polymorphisms in IL4 and IL4RA genes have been described. Particularly, -33C>TIL4 and 576Q>RIL4RA SNPs have been independently associated t...

    Authors: María Isidoro-García, Ignacio Dávila, Elena Laffond, Esther Moreno, Félix Lorente and Rogelio González-Sarmiento
    Citation: Clinical and Molecular Allergy 2005 3:15
    Content type: Research Published on:

  19. Allergic sensitization and reactions to guinea pig (Cavia porcellus) have been well documented in laboratory animal handlers, primarily manifesting as rhinitis, conjunctivitis, and asthma. Severe allergic reactio...

    Authors: Michael C Zacharisen, Michael B Levy, Jeffrey L Shaw and Viswanath P Kurup
    Citation: Clinical and Molecular Allergy 2005 3:14
    Content type: Case Report Published on:

  20. Profilins are highly cross-reactive allergens which bind IgE antibodies of almost 20% of plant-allergic patients. This study is aimed at investigating cross-reactivity of melon profilin with other plant profil...

    Authors: Mojtaba Sankian, Abdolreza Varasteh, Nazanin Pazouki and Mahmoud Mahmoudi
    Citation: Clinical and Molecular Allergy 2005 3:13
    Content type: Research Published on:

  21. Previously we treated patients with insect sting allergy with venom immunotherapy (IT) using whole body insect extracts. From 1980 we changed to insect venoms. The purpose of this study was to analyse data fro...

    Authors: Rolf Haye and Liv Kari Døsen
    Citation: Clinical and Molecular Allergy 2005 3:12
    Content type: Research Published on:

  22. In recent years, allergy to natural rubber latex has emerged as a major allergy among certain occupational groups and patients with underlying diseases. The sensitization and development of latex allergy has b...

    Authors: Viswanath P Kurup, Gordon L Sussman, Hoong Y Yeang, Nancy Elms, Heimo Breiteneder, Siti AM Arif, Kevin J Kelly, Naveen K Bansal and Jordan N Fink
    Citation: Clinical and Molecular Allergy 2005 3:11
    Content type: Research Published on:

  23. The basophil activation test (BAT), in which translocation of markers to the surface of blood basophils is measured in response to allergen by flow cytometry, is a rapid assay that is gaining popularity. Two m...

    Authors: Hans Jürgen Hoffmann, Mette Bøgebjerg, Lars Peter Nielsen and Ronald Dahl
    Citation: Clinical and Molecular Allergy 2005 3:10
    Content type: Research Published on:

  24. The diagnosis of immediate allergy is mainly based upon an evocative clinical history, positive skin tests (gold standard) and, if available, detection of specific IgE. In some complicated cases, functional in vi...

    Authors: Radhia Boumiza, Anne-Lise Debard and Guillaume Monneret
    Citation: Clinical and Molecular Allergy 2005 3:9
    Content type: Review Published on:

  25. Animal-derived allergens include lipocalins which play an increasing role in occupational respiratory sensitizations. The prevention of sensitization in stock farming is often difficult due to intense exposure...

    Authors: Gintautas Korinth, Horst Christoph Broding, Wolfgang Uter and Hans Drexler
    Citation: Clinical and Molecular Allergy 2005 3:8
    Content type: Case Report Published on:

  27. Airway smooth muscle cells play a key role in remodeling that contributes to airway hyperreactivity. Airway smooth muscle remodeling includes hypertrophy and hyperplasia. It has been previously shown that the ...

    Authors: Joseph T Belleau, Radha K Gandhi, Holly M McPherson and D Betty Lew
    Citation: Clinical and Molecular Allergy 2005 3:6
    Content type: Research Published on:

  30. A circadian rhythm of symptoms has been reported in allergic rhinitis and some studies have shown the dosing time of antihistamines to be of importance for optimizing symptom relief in this disease. The object...

    Authors: Rolf Haye, Kjetil Høye, Olof Berg, Sissel Frønes and Tone Ødegård
    Citation: Clinical and Molecular Allergy 2005 3:3
    Content type: Research Published on:

  31. Asthma and sickle cell disease are common conditions that both may result in pulmonary complications. We hypothesized that children with sickle cell disease with concomitant asthma have an increased incidence ...

    Authors: Mark E Nordness, John Lynn, Michael C Zacharisen, Paul J Scott and Kevin J Kelly
    Citation: Clinical and Molecular Allergy 2005 3:2
    Content type: Research Published on:

  32. Beauveria bassiana is an important entomopathogenic fungus currently under development as a bio-control agent for a variety of insect pests. Although reported to be non-toxic to vertebrates, the potential allerge...

    Authors: Greg S Westwood, Shih-Wen Huang and Nemat O Keyhani
    Citation: Clinical and Molecular Allergy 2005 3:1
    Content type: Research Published on:

  35. Osteoporosis or osteopenia occurs in about 44 million Americans, resulting in 1.5 million fragility fractures per year. The consequences of these fractures include pain, disability, depression, loss of indepen...

    Authors: E Michael Lewiecki
    Citation: Clinical and Molecular Allergy 2004 2:9
    Content type: Review Published on:

  36. A computerized statistical analysis of allergy skin test results correlating patient reactivities initiated our interest in the cross-reactive allergens of mesquite tree pollen. In-vitro testing with mesquite-...

    Authors: Sue Killian and John McMichael
    Citation: Clinical and Molecular Allergy 2004 2:8
    Content type: Research Published on:

  37. Eosinophilic gastritis is related to eosinophilic gastroenteritis, varying only in regards to the extent of disease and small bowel involvement. Common symptoms reported are similar to our patient's including:...

    Authors: Billy H Copeland, Omolola O Aramide, Salim A Wehbe, S Matthew Fitzgerald and Guha Krishnaswamy
    Citation: Clinical and Molecular Allergy 2004 2:7
    Content type: Case Report Published on:

  38. A number of reports indicate that circulating immune complexes (CIC) and activation of the complement system contribute to the pathogenesis of Type I allergy. The aim of this study was to investigate the statu...

    Authors: Alexander M Abdelnoor, Firas Kobeissy, Daad Farhat and Usamah Hadi
    Citation: Clinical and Molecular Allergy 2004 2:6
    Content type: Research Published on:

  39. Tinea pedis is a chronic fungal infection of the feet, very often observed in patients who are immuno-suppressed or have diabetes mellitus. The practicing allergist may be called upon to treat this disease for...

    Authors: Muhannad Al Hasan, S Matthew Fitzgerald, Mahnaz Saoudian and Guha Krishnaswamy
    Citation: Clinical and Molecular Allergy 2004 2:5
    Content type: Review Published on:

  40. Macrolides, a class of antimicrobials isolated from Streptomycetes more than 50 years ago, are used extensively to treat sinopulmonary infections in humans. In addition, a growing body of experimental and clin...

    Authors: Umur HatipoÄŸlu and Israel Rubinstein
    Citation: Clinical and Molecular Allergy 2004 2:4
    Content type: Review Published on:

  41. We previously demonstrated in a group of patients with perennial allergic rhinitis alone impairment of spirometric parameters and high percentage of subjects with bronchial hyperreactivity (BHR). The present s...

    Authors: Giorgio Ciprandi, Ignazio Cirillo, Maria A Tosca and Andrea Vizzaccaro
    Citation: Clinical and Molecular Allergy 2004 2:3
    Content type: Research Published on:

  42. Past few years cranberry/lingonberry products have been incorporated as healthy products to the US and European market as prophylaxis of recurrent urinary tract infections in young women as well as in chronic ...

    Authors: Victor Matheu, Maria L Baeza, Jose M Zubeldia and Yvelise Barrios
    Citation: Clinical and Molecular Allergy 2004 2:2
    Content type: Case Report Published on:

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Clinical and Molecular Allergy

ISSN: 1476-7961

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