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Research
Sublingual immunotherapy (SLIT) is a feasible option to classical subcutaneous immunotherapy to treat respiratory allergy and is increasingly prescribed in Europe. However, the lack of reimbursement may limit ...
Clinical and Molecular Allergy 2017 15:15
Published on: 15 August 2017
Case Report
Hypersensitivity is a rare adverse drug reaction (ADR) associated with anti-epileptic medications. Phenytoin is one of the commonly used drugs for treatment of epilepsy that encounters a hypersensitivity react...
Clinical and Molecular Allergy 2017 15:14
Published on: 15 June 2017
Review
Allergen immunotherapy (AIT) is the only treatment that works on the causes of allergy. Available AIT nowadays are subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) for allergic rhinitis an...
Clinical and Molecular Allergy 2017 15:13
Published on: 15 June 2017
Review
Recently, some studies demonstrated that HMGB1, as proinflammatory mediator belonging to the alarmin family, has a key role in different acute and chronic immune disorders. Asthma is a complex disease characte...
Clinical and Molecular Allergy 2017 15:12
Published on: 14 June 2017
Research
In Europe more than 50% of asthmatic treated patients have not well-controlled asthma. Asthma affects about 2.5 million of patients in Italy.
Clinical and Molecular Allergy 2017 15:11
Published on: 8 May 2017
Research
Early recognition of inflammatory markers and their relation to asthma, adverse drug reactions, allergic rhinitis, atopic dermatitis and other allergic diseases is an important goal in allergy. The vast majori...
Clinical and Molecular Allergy 2017 15:10
Published on: 13 April 2017
Review
Hypersensitivity to para-phenylenediamine (PPD) and related compounds induced by temporary black henna tattoos has become a serious health problem worldwide. Different patterns of sensitization with various cl...
Clinical and Molecular Allergy 2017 15:8
Published on: 10 April 2017
Commentary
Even if severe asthma (SA) accounts for 5–10% of all cases of the disease, it is currently a crucial unmet need, owing its difficult clinical management and its high social costs. For this reason several netwo...
Clinical and Molecular Allergy 2017 15:9
Published on: 10 April 2017
Research
Allergen-specific immunotherapy (AIT) is the only treatment able to change the natural course of allergic diseases. We aimed at investigating the clinical efficacy of SLITOR (Serbian registered vaccine for sub...
Clinical and Molecular Allergy 2017 15:7
Published on: 3 April 2017
Review
Allergic rhinitis has a very high burden regarding both direct and indirect costs. This makes essential in the management of AR to reduce the clinical severity of the disease and thus to lessen its costs. This...
Clinical and Molecular Allergy 2017 15:5
Published on: 7 March 2017
Review
Hypersensitivity pneumonitis (HP), also called extrinsic allergic alveolitis, is a respiratory syndrome involving the lung parenchyma and specifically the alveoli, terminal bronchioli, and alveolar interstitiu...
Clinical and Molecular Allergy 2017 15:6
Published on: 7 March 2017
Research
Multiple sensitizations in early age have been reported to be a risk for development of asthma. This study evaluates the emergence and evolution of IgE to aeroallergens among a cohort of children with physicia...
Clinical and Molecular Allergy 2017 15:4
Published on: 3 March 2017
Case Report
Bronchial asthma is a heterogeneous respiratory condition which can be mimicked by a wide range of pathologies including upper airways stenosis. The accurate diagnosis of asthma, as with other conditions, may ...
Clinical and Molecular Allergy 2017 15:3
Published on: 8 February 2017
Review
Life expectancy and the number of elderly people are progressively increasing around the world. Together with other pathologies, allergic diseases also show an increasing incidence in geriatric age. This is pa...
Clinical and Molecular Allergy 2017 15:2
Published on: 3 February 2017
Research
Sublingual immunotherapy has been proven as a well-tolerated and effective treatment for allergic rhinitis. Within this type of treatment, GRAZAX® is the most documented product in terms of safety and efficacy. T...
Clinical and Molecular Allergy 2017 15:1
Published on: 6 January 2017
Review
The tapeworm Taenia (T.) solium can be responsible for two different conditions: taeniasis and cysticercosis. Helminth infections in human host cause an immune response associated with elevated levels of IgE, tis...
Clinical and Molecular Allergy 2016 14:18
Published on: 7 December 2016
Review
Eosinophilic diseases of the gastrointestinal tract, including eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE), are rare chronic pathologies of the digestive system, with an immuno-mediat...
Clinical and Molecular Allergy 2016 14:17
Published on: 1 December 2016
Research
CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that ch...
Clinical and Molecular Allergy 2016 14:16
Published on: 8 November 2016
Research
The Nef protein can be detected in plasma of HIV-1-infected patients and plays a role in the pathogenesis of HIV-1. Nef produced during the early stages of infection is fundamental in creating the ideal enviro...
Clinical and Molecular Allergy 2016 14:15
Published on: 1 November 2016
Case Report
Systemic reactions (SR) to venom immunotherapy (VIT) are rare but may occur, with a rate significantly higher for honeybee than for vespid VIT. In patients with repeated SRs to VIT it is difficult to reach the...
Clinical and Molecular Allergy 2016 14:14
Published on: 24 October 2016
Case Report
Systemic sclerosis (SSc) is a complex autoimmune disease characterized by vascular alterations and autoimmune activation leading to widespread organ fibrosis. At the early stage of disease when organ involveme...
Clinical and Molecular Allergy 2016 14:13
Published on: 11 October 2016
Review
This meta-analysis compared the health-related quality of life (HRQL) of patients with allergic rhinitis (AR) and/or allergic asthma (AA) caused by perennial house dust mite (HDM) versus AR and/or AA caused by...
Clinical and Molecular Allergy 2016 14:12
Published on: 28 September 2016
Review
Autoimmune disorders are characterized by tissue damage, caused by self-reactivity of different effectors mechanisms of the immune system, namely antibodies and T cells. Their occurrence may be associated with...
Clinical and Molecular Allergy 2016 14:11
Published on: 15 September 2016
Review
The oral mucosa including the lips is constantly exposed to several noxious stimuli, irritants and allergens. However, oral contact pathologies are not frequently seen because of the relative resistance of the...
Clinical and Molecular Allergy 2016 14:10
Published on: 1 September 2016
Review
Drug induced exfoliative dermatitis (ED) are a group of rare and severe drug hypersensitivity reactions (DHR) involving skin and usually occurring from days to several weeks after drug exposure. Erythema multi...
Clinical and Molecular Allergy 2016 14:9
Published on: 22 August 2016
The official journal of the Italian Society of Allergology, Asthma and Clinical Immunology (SIAAIC)
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