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Table 1 Main demographic, clinical, and laboratory characteristics of the 14 included patients

From: High prevalence of sensitization to non-specific lipid transfer protein in adult patients with primary eosinophilic gastrointestinal disorders in Italy: a single center series

Parameter

Result

Male sex, n (%)

12 (85.7)

Age, median (IQR; years)

41 (25–48)

Type of EGID

EoE (n = 6) EGE (n = 1) EC (n = 7)

Time since diagnosis, median (IQR; years)

EoE: 1 (0.25–1) EGE: 3 EC: 1.5 (1–4.5)

Tissue eosinophils at diagnosis, median (IQR; n/HPF)

EoE: 64 (30–95) EGE: 114 EC: 100 (100–107)

Blood eosinophils at diagnosis, median (IQR; cells/microL)

300 (180–330)

Serum ECP, median (IQR; U/mL)

28 (11.0–62.7) (11/14)

Main gastrointestinal symptoms at onset, n (%)

EoE: dysphagia, reflux, 4 (66.7) EGE: dyspepsia EC: abdominal pain, 5 (71.4)

Allergic comorbidities and sensitization profile

Atopya, n (%)

11 (78.5)

Allergic rhinitis, n (%)

10 (71.4)

Asthma, n (%)

2 (14.2)

Atopic dermatitis, n (%)

2 (14.2)

Food allergy, n (%)

5 (35.7)

Drug allergy, n (%)

2 (14.2)

Hymenoptera venom allergy, n (%)

1 (7.1)

PR-10b, n (%)

3 (21.3)

LTPb, n (%)

7 (50.0)

Profilinb, n (%)

2 (14.2)

IgE level, median (IQR; kU/L)

173 (112–417)

  1. EC eosinophilic colitis, ECP eosinophilic cationic protein, EoE eosinophilic esophagitis, EGE eosinophilic gastritis, HPF high power field, IQR interquartile range, LTP lipid transfer protein, PR-10, pathogenesis-related-protein-10
  2. awhen at least one allergy was present
  3. bassessed with specific IgE