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Fig. 8 | Clinical and Molecular Allergy

Fig. 8

From: Impact of oligomerization on the allergenicity of allergens

Fig. 8

The dimer formation of the allergen on a mast cell. Individual allergens that present only one epitope, disable to cross-link the FcεRI-bound IgE antibodies (left). The increase of the local concentration of the allergen on a mast cell can increase the dimerization of allergens, leading to the cross-linking of FcεRI-bound IgE antibodies (right)

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