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Fig. 2 | Clinical and Molecular Allergy

Fig. 2

From: The effect of vitamin D, magnesium and zinc supplements on interferon signaling pathways and their relationship to control SARS-CoV-2 infection

Fig. 2

a recruitment of activated neutrophils into the inflamed interstitium and alveolar space by cytokines and chemokines secreted from infected epithelial and endothelial cells and activated alveolar macrophages; b cytokines and chemokines secreted by activated leukocytes cause cytokine and chemokine storms that are involved in the pathogenesis of ARDS; C dysregulation in homeostasis resulted in intra-alveolar or systemic fibrin clots and thrombotic complications. In each mentioned complication, the positive effects of VitD on the prevention and improvement of viral infections have been demonstrated

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