Skip to main content

Table 1 Estimation of patients with severe uncontrolled asthma in Italy

From: Defining type 2 asthma and patients eligible for dupilumab in Italy: a biomarker-based analysis

#

Group of subjects

Estimation

Number of subjects (N)

Source

1

Italian population, ≥ 12 years

–

5,41,19,490

ISTAT 2019 [43]

2

Patients with asthma

6.10% of #1

33,01,289

[41]

3

Patients with asthma exemption code

36.29% of #2

11,97,821

4

Patients with spirometry (last 12 months)

27.74% of #3

3,32,281

5

Patients treated with ICS

46.95% of #4

1,55,997

6

Patients treated with high-dose ICS

43.05% of #5

67,151

7

Patients treated with high-dose ICS, adherent

57.20% of #6

38,410

8

Uncontrolled patients with ≥ 2 exacerbations/year*

47.57% of #7

18,270

9

Uncontrolled patients with severe asthma

0.04% of #1

21,649

[39]

10

Average number uncontrolled patients

with severe asthma

Average of #8 and #9

19,960

Calculated

  1. ICS inhaled corticosteroids, ISTAT italian institute of statistics
  2. *Corresponding to 0.034% of the Italian population, ≥ 12 years (#1)