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Fig. 3 | Clinical and Molecular Allergy

Fig. 3

From: Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite

Fig. 3

Effect of specific antigen on release of IL-17, IL-5 and IFN-γ in peripheral blood mononuclear cells (PBMCs) of HDM+ allergic rhinitis (AR) patients or healthy controls. a Stimulation of PBMCs of monosensitized HDM+AR patients and control subject with house dust mite (HDM) (n = 6); b Stimulation of PBMC of monosensitized HDM+AR patients (n = 8) and control subjects (n = 5) with mugwort; c The positive ratio of cytokine produced by PBMCs of monosensitized HDM+AR or controls upon HDM and mugwort stimulation. d Concentrations of IL-17, IL-5 and IFN-γ released in PBMCs from HDM+AR patients stimulated with synthesized tropomyosin peptides of mugwort and Der p10 (n = 4). e Concentration of IL-17, IL-5 and IFN-γ released in PBMCs of mugwort+AR patients with mugwort, synthetic tropomyosin peptide of mugwort, house dust mite (HDM), tropomyosin of HDM Der p10 stimulations (n = 1)

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