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Fig. 2 | Clinical and Molecular Allergy

Fig. 2

From: Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite

Fig. 2

a Concentrations of house dust mite (HDM)-specific IgE in the serum of HDM+ allergic rhinitis (AR) patients (n = 15) incubated in the absence or presence of synthesized tropomyosin peptides of mugwort; b Synthetic tropomyosin peptide of Artemisia sieversian (A. sieversian,) inhibits IgE-binding to Dermatophagoides pteronyssinus 10 (Der p10) measuring by ELISA. Tropomyosin of mugwort exhibits inhibitory effect in 4 out of 8 patients at the concentration of 50 ng/mL. c The expression of basophils (CCR3+CD123+CD63+) with stimulations of Der p10 and synthetic tropomyosin peptide of mugwort. Totally, HDM specific IgE pre-incubated basophils from 2 out of 8 patients were activated by tropomyosin of mugwort

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Clinical and Molecular Allergy

ISSN: 1476-7961

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