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Table 2 Risk stratification according to the patients’ characteristics

From: SIRM-SIAAIC consensus, an Italian document on management of patients at risk of hypersensitivity reactions to contrast media

Group Risk factors Level of risk Allergy evaluation for CM
0 Female gender [19]
Atopy [19]
Intravascular CM injection [23]
Severe cardiovascular disease [23]
Viral infection and autoimmune diseases [1]
Psychiatric disorders [23]
Interleukin-2 treatment and contact allergy (for NIHRs) [2]
Treatment with ACE-inhibitors, beta-blockers, or proton pump inhibitors (for IHRS) [19]
Food allergy [23]
Drug allergy [24]
Concomitant allergic disease [23]
Allergy to iodine-containing antiseptics [25]
Very low (not relevant) No
1 Uncontrolled asthma [21, 22]
Active urticaria-angioedema [2, 22]
Mastocytosis [19]
Recurrent angioedema
Idiopathic anaphylaxis
Medium No
2 History of hypersensitivity reactions to contrast media of the same class of the one to be administered [1, 7, 17, 18, 20] High Yes