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Table 1 Most common first and second-generation antihistamines

From: Cetirizine use in childhood: an update of a friendly 30-year drug

First generationSecond generation
DiphenhydramineCetirizine
ClemastineLevocetirizine
ClorphenamineKetotifen
DimetindeneLoratadine
HydroxyzineDesloratadine
PromethazineRupatadine
AlimemazineEbastine
CyproheptadineBilastine
 Fexofenadine