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Table 4 Associations between allergens and severity disease diagnosed by component-resolved diagnostics

From: Sensitization profile in patients with respiratory allergic diseases: differences between conventional and molecular diagnosis (a cross-sectional study)

  Asthmaa Rhinitis
Mild (N = 18) Moderate-severe (N = 7) p Mild (N = 59) Moderate-severe (N = 36) p
House dust mites
 Der p 1 11 (68.8) 4 (57.1) 0.657 25 (43.1) 17 (47.2) 0.831
 Der p 2 12 (75.0) 4 (57.1) 0.626 25 (43.1) 26 (72.2) 0.010
 Der f 1 11 (68.8) 4 (57.1) 0.657 23 (39.7) 16 (44.4) 0.672
 Der f 2 12 (75.0) 3 (42.9) 0.182 25 (43.1) 25 (69.4) 0.019
 Lep d 2 7 (43.8) 3 (42.9) 1.000 7 (12.1) 12 (33.3) 0.018
Pollens
 Ole e 1 9 (60.0) 4 (57.1) 1.000 25 (43.1) 14 (41.2) 1.000
 Ole e 9 1 (6.3) 0 (0.0) 1.000 1 (1.7) 1 (2.8) 1.000
 Art v 1 1 (6.3) 0 (0.0) 1.000 5 (8.8) 4 (11.1) 0.731
 Pla l 1 0 (0.0) 0 (0.0) 2 (3.4) 3 (8.3) 0.368
 Phl p 1 7 (43.8) 1 (14.3) 0.345 17 (29.3) 16 (44.4) 0.183
 Phl p 5 1 (6.3) 0 (0.0) 1.000 6 (10.3) 5 (13.9) 0.744
 Pla a 1 + 2 0 (0.0) 1 (14.3) 0.304 4 (6.9) 1 (2.8) 0.646
 Par j 2 2 (12.5) 2 (28.6) 0.557 8 (14) 7 (19.4) 0.567
 Sal k 1 0 (0.0) 0 (0.0) 1 (1.7) 2 (5.6) 0.556
 Cup s 1 1 (6.3) 1 (16.7) 0.480 6 (10.5) 3 (8.3) 1.000
Molds
 Alt a 1 2 (12.5) 1 (14.3) 1.000 9 (15.5) 9 (25.0) 0.289
Panallergens
 Pho d 2       
 Che a 3       
 Pru p 3       
 Der p 10 0 (0.0) 1 (16.7) 0.273 0 (0.0) 2 (5.6) 0.147
 Pen a 1 1 (6.3) 0 (0.0) 1.000 2 (3.4) 2 (5.7) 0.630
  1. p values in italics correspond to significant differences at a bilateral alpha value of 0.05
  2. Positive sensitizations, No. (%)
  3. aWith or without concomitant rhinitis