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Table 4 Associations between allergens and severity disease diagnosed by component-resolved diagnostics

From: Sensitization profile in patients with respiratory allergic diseases: differences between conventional and molecular diagnosis (a cross-sectional study)

 

Asthmaa

Rhinitis

Mild (N = 18)

Moderate-severe (N = 7)

p

Mild (N = 59)

Moderate-severe (N = 36)

p

House dust mites

 Der p 1

11 (68.8)

4 (57.1)

0.657

25 (43.1)

17 (47.2)

0.831

 Der p 2

12 (75.0)

4 (57.1)

0.626

25 (43.1)

26 (72.2)

0.010

 Der f 1

11 (68.8)

4 (57.1)

0.657

23 (39.7)

16 (44.4)

0.672

 Der f 2

12 (75.0)

3 (42.9)

0.182

25 (43.1)

25 (69.4)

0.019

 Lep d 2

7 (43.8)

3 (42.9)

1.000

7 (12.1)

12 (33.3)

0.018

Pollens

 Ole e 1

9 (60.0)

4 (57.1)

1.000

25 (43.1)

14 (41.2)

1.000

 Ole e 9

1 (6.3)

0 (0.0)

1.000

1 (1.7)

1 (2.8)

1.000

 Art v 1

1 (6.3)

0 (0.0)

1.000

5 (8.8)

4 (11.1)

0.731

 Pla l 1

0 (0.0)

0 (0.0)

2 (3.4)

3 (8.3)

0.368

 Phl p 1

7 (43.8)

1 (14.3)

0.345

17 (29.3)

16 (44.4)

0.183

 Phl p 5

1 (6.3)

0 (0.0)

1.000

6 (10.3)

5 (13.9)

0.744

 Pla a 1 + 2

0 (0.0)

1 (14.3)

0.304

4 (6.9)

1 (2.8)

0.646

 Par j 2

2 (12.5)

2 (28.6)

0.557

8 (14)

7 (19.4)

0.567

 Sal k 1

0 (0.0)

0 (0.0)

1 (1.7)

2 (5.6)

0.556

 Cup s 1

1 (6.3)

1 (16.7)

0.480

6 (10.5)

3 (8.3)

1.000

Molds

 Alt a 1

2 (12.5)

1 (14.3)

1.000

9 (15.5)

9 (25.0)

0.289

Panallergens

 Pho d 2

      

 Che a 3

      

 Pru p 3

      

 Der p 10

0 (0.0)

1 (16.7)

0.273

0 (0.0)

2 (5.6)

0.147

 Pen a 1

1 (6.3)

0 (0.0)

1.000

2 (3.4)

2 (5.7)

0.630

  1. p values in italics correspond to significant differences at a bilateral alpha value of 0.05
  2. Positive sensitizations, No. (%)
  3. aWith or without concomitant rhinitis