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Table 2 Multivariate analysis of predictors of poor control, lower lung function and sputum eosinophilia

From: Comorbidities are associated with different features of severe asthma

Indipendent variables Dependent variables OR (95% CI)
Poor symptom control Lower lung function Sputum eosinophilia ≥ 3%
Age (> vs < median value) 0.7 (0.2–1.9) 0.8 (0.3–2.5) 0.2 (0.0–1.3)
Gender (F vs M) 0.87 (0.3–2.8) 0.3 (0.1–0.9)* 1.6 (0.2–12.1)
Smoke (Yes vs No-Ex) 0.4 (0–4.9) 0.3 (0.0–4.0) 0.5 (0.0–18.7)
Duration of asthma (> vs < median value) 1.9 (0.6–6.1) 5.1 (1.4–18.8)* 0.1 (0.01–0.5)*
Obesity (Y vs N) 4.9 (1.6–15.4)* 1.6 (0.5–4.9) 0.6 (0.1–2.8)
CRSwNP (Yes vs N) 0.9 (0.3–2.7) 2.9 (1–9.1)§ 16.2 (1.7–151.7)*
GERD (Yes vs N) 1.4 (0.5–4.2) 0.5 (0.2–1.8) 0.6 (0.1–2.9)
  1. CRSwP chronic rhinosinusitis with nasal polyps, GERD gastro-esophageal reflux disease
  2. * p < 0.05; § p = 0.06