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Table 2 Multivariate analysis of predictors of poor control, lower lung function and sputum eosinophilia

From: Comorbidities are associated with different features of severe asthma

Indipendent variables

Dependent variables

OR (95% CI)

Poor symptom control

Lower lung function

Sputum eosinophilia ≥ 3%

Age

(> vs < median value)

0.7 (0.2–1.9)

0.8 (0.3–2.5)

0.2 (0.0–1.3)

Gender

(F vs M)

0.87 (0.3–2.8)

0.3 (0.1–0.9)*

1.6 (0.2–12.1)

Smoke

(Yes vs No-Ex)

0.4 (0–4.9)

0.3 (0.0–4.0)

0.5 (0.0–18.7)

Duration of asthma

(> vs < median value)

1.9 (0.6–6.1)

5.1 (1.4–18.8)*

0.1 (0.01–0.5)*

Obesity

(Y vs N)

4.9 (1.6–15.4)*

1.6 (0.5–4.9)

0.6 (0.1–2.8)

CRSwNP

(Yes vs N)

0.9 (0.3–2.7)

2.9 (1–9.1)§

16.2 (1.7–151.7)*

GERD

(Yes vs N)

1.4 (0.5–4.2)

0.5 (0.2–1.8)

0.6 (0.1–2.9)

  1. CRSwP chronic rhinosinusitis with nasal polyps, GERD gastro-esophageal reflux disease
  2. * p < 0.05; § p = 0.06