Fig. 1

Filaggrin in pediatric patients with atopic dermatitis, allergic rhinitis and bronchial asthma. a Levels of human filaggrin (FLG) in the sera of all studied atopic pediatric patients (n = 395) and non-atopic pediatric controls (n = 410). *p < 0.01 versus all tested atopic patients. b Levels of human FLG in the patients’ sera of atopic dermatitis pediatric patients (AD Ped. Patients; n = 130) and non-atopic pediatric controls (n = 410). ^#p < 0.001 versus AD Ped. Patients. c Levels of human FLG in the patients’ sera of allergic rhinitis pediatric patients (AR pediatric patients; n = 120) and non-atopic pediatric controls (n = 410). ^#p < 0.001 versus AR pediatric patients. d Levels of human FLG in the patients’ sera of bronchial asthma pediatric patients (BA Ped. Patients; n = 145) and non-atopic pediatric controls (n = 410). ^#p < 0.01 versus AR Ped. Patients