Table 1 Patient characteristics according to the rs4950928 genotype
From: Role of genetic variations of chitinase 3-like 1 in bronchial asthmatic patients
rs4950928 genotype | CC (n = 270) | CG (n = 90) | GG (n = 21) | P value |
|---|---|---|---|---|
Age, years | 57.6 ± 1.0 | 58.5 ± 1.7 | 55.8 ± 3.7 | NS |
Height, cm | 158.4 ± 0.6 | 159.1 ± 1.0 | 160.4 ± 2.1 | NS |
Body weight, kg | 59.4 ± 0.7 | 60.7 ± 1.2 | 60.8 ± 2.7 | NS |
Sex, n (%) | 110 men (41) | 41 men (46) | 12 men (57) | NS |
Age of onset, years | 42.5 ± 1.3 | 44.3 ± 2.2 | 31.1 ± 4.5 | 0.032 |
Eosinophil count/μL | 300.9 ± 17.4 | 359.5 ± 29.9 | 277.6 ± 65.1 | NS |
IgE level, IU/mL | 412.1 ± 58.0 | 435.2 ± 77.9 | 565.4 ± 233.2 | NS |
GINA asthma severity, n (%) | ||||
 Mild | 58 (21.5) | 21 (23.3) | 6 (28.6) | – |
 Moderate | 105 (38.9) | 33 (36.7) | 12 (57.1) | – |
 Severe | 107 (39.6) | 36 (40.0) | 3 (14.3) | – |
Pulmonary function | ||||
 %FVC | 103.3 ± 2.0 | 104.3 ± 3.4 | 103.51 ± 9.8 | NS |
 FEV1, L | 2.3 ± 0.1 | 2.3 ± 0.1 | 2.3 ± 0.2 | NS |
 FEV1/FVC, % | 72.9 ± 0.7 | 70.8 ± 1.2 | 70.2 ± 2.6 | NS |
 %FEV1 | 98.9 ± 1.5 | 98.8 ± 2.6 | 95.1 ± 5.3 | NS |
  Mild | 105.8 ± 3.1 | 106.8 ± 5.4 | 91.0 ± 26.5 | – |
  Moderate | 100.0 ± 2.3 | 100.5 ± 4.3 | 103.3 ± 22.6 | – |
  Severe | 94.2 ± 2.3 | 92.5 ± 4.1 | 92.2 ± 33.1 | – |
 Equivalent FP CFC dose (μg/day) | 382.1 ± 17.0 | 362.4 ± 29.3 | 228.0 ± 63.7 | NS |