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Table 2 Demographic and medical data of patients who suffered from HDR

From: Importance of hypersensitivity in adverse reactions to drugs in the elderly

Feature

Patients aged ≥ 65 year

n. (%)

Patients aged < 65 year

n. (%)

Χ2

Female

101 (80.15%)

42 (64.61%)

0.019

Family history of atopy

0

4 (6.1%)

0.005

Allergic diseases

5 (3.96%)

16 (24.61%)

0.000

Previous ADRs

12 (9.5%)

15 (23.07%)

0.01

Smoker

38 (30.15%)

22 (33.8%)

0.603

Alcohol abuse

19 (15%)

6 (9.23%)

0.256

Multiple chronic drug regimen

109 (86.5%)

20 (30.7%)

0.000

Comorbidities

126 (100%)

6 (9.23%)

0.000

Use of self-medications

31 (24.6%)

22 (33.8%)

0.176

Short course therapy with ≥ 3 drugs

48 (38%)

18 (27.6%)

0.152

Total

126 (100%)

65 (100%)