Fig. 2

Kinetics of Vespula-specific IgE. a Kinetics of the bound pool of Vespula-specific IgE assessed by quantitative intradermal skin testing, at the indicated time-points (months). Skin Index represents the ratio between the area of the allergen wheal and the area of the exogenous histamine reference wheal. Intradermal skin tests were performed with a 0.1 μg/ml concentration of Vespula venom. Time-points on x-axis are averages of individual time-point. b Kinetics of circulating pool of Vespula-specific IgE measured using RAST, at the indicated time-points (months; averages of individual time-points). Results are expressed as mean ± SEM. Statistical significance against baseline time-point was calculated by one-way Anova with Bonferroni post-test (N.S.: > 0.01, *p < 0.01, **p < 0.001). Dashed vertical line separates the VIT course from the follow-up