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Table 1 Considerations, unmet needs and challenges in implementing treatment guidelines for allergic rhinitis and urticaria

From: Selecting optimal second-generation antihistamines for allergic rhinitis and urticaria in Asia

 

Allergic rhinitis

Urticaria

Common adult patient profiles

Adults, some with comorbidities (e.g., asthma)

20‒40-year-old adults

Pregnant/lactating women

Unmet needs

Inadequate diagnosis

Inadequate control of symptoms

Lack of long-acting, non-sedative drugs (limited availability)

Lack of rest (limited quality of sleep)

Requirement of additional tools for diagnosis (lack of guideline education and availability of tests for specific urticaria subtypes)a

Inadequate control of symptoms

A single drug with all preferred features of an antihistamine

Lack of rest (limited quality of sleep)

Challenges in implementation of existing guidelines

Patient awareness

Doctor awareness

Institutional practices and drug availability

Practical considerations in treatment

Patient and doctor education

Patient profile (e.g., renal/hepatic impairment, age, concomitant disease)

Financial constraints

Considerations of taking antihistamines by special populations, such as elderly patients and pregnant or breastfeeding women

Lack of patient compliance

Considerations of taking antihistamines by special populations, such as elderly patients and pregnant or breastfeeding women

Patient profile (e.g., renal/hepatic impairment, age, concomitant disease)

Financial constraints

Limitations in treatment

Patient preferences (demand for a treatment that will restore their QoL)

Patient preferences (demand for a treatment that will restore their QoL)

  1. Data presented in this table reflect results from completed surveys and consensual agreement from authors
  2. QoL quality of life
  3. aAncillary tests to diagnose autoimmune urticaria (anti-FCeR1 receptor) and other subtypes of urticaria (i.e. cold urticaria) are not available in parts of the Asia Pacific region