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Table 1 Considerations, unmet needs and challenges in implementing treatment guidelines for allergic rhinitis and urticaria

From: Selecting optimal second-generation antihistamines for allergic rhinitis and urticaria in Asia

  Allergic rhinitis Urticaria
Common adult patient profiles Adults, some with comorbidities (e.g., asthma) 20‒40-year-old adults
Pregnant/lactating women
Unmet needs Inadequate diagnosis
Inadequate control of symptoms
Lack of long-acting, non-sedative drugs (limited availability)
Lack of rest (limited quality of sleep)
Requirement of additional tools for diagnosis (lack of guideline education and availability of tests for specific urticaria subtypes)a
Inadequate control of symptoms
A single drug with all preferred features of an antihistamine
Lack of rest (limited quality of sleep)
Challenges in implementation of existing guidelines Patient awareness
Doctor awareness
Institutional practices and drug availability
Practical considerations in treatment Patient and doctor education
Patient profile (e.g., renal/hepatic impairment, age, concomitant disease)
Financial constraints
Considerations of taking antihistamines by special populations, such as elderly patients and pregnant or breastfeeding women
Lack of patient compliance
Considerations of taking antihistamines by special populations, such as elderly patients and pregnant or breastfeeding women
Patient profile (e.g., renal/hepatic impairment, age, concomitant disease)
Financial constraints
Limitations in treatment Patient preferences (demand for a treatment that will restore their QoL) Patient preferences (demand for a treatment that will restore their QoL)
  1. Data presented in this table reflect results from completed surveys and consensual agreement from authors
  2. QoL quality of life
  3. aAncillary tests to diagnose autoimmune urticaria (anti-FCeR1 receptor) and other subtypes of urticaria (i.e. cold urticaria) are not available in parts of the Asia Pacific region