Hypersensitivity reactions due to black henna tattoos and their components: are the clinical pictures related to the immune pathomechanism?

Table 1 Reactions to black henna tattoo: main clinical manifestations and time to onset after the application

Clinical manifestation	Time to onset	Ref
Eczematous contact dermatitis	1–2 days	[11, 49, 50]
Lichenoid eruptions	1–2 weeks	[11, 51, 52]
Contact urticaria and angioneurotic oedema	Few hours–2 days	[19, 33, 34]
Contact anaphylaxis	Few hours	[20]
Lymphomatoid reactions	Few hours–few days	[53, 54]
Vesicular-bullous lesions	1–4 days	[55, 56]
Erythema multiforme like eruptions	2–14 days	[58,59,60]
Sweet syndrome	3 days	[63]
Wells syndrome	3 days	[64, 65]
Prurigo nodularis	3 months	[66]
Connubial contact dermatitis	Few days	[67, 68]

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