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Fig. 3 | Clinical and Molecular Allergy

Fig. 3

From: Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients

Fig. 3

CHI3L1 levels positively correlate with the frequency of CD161+ cells in the SF of JIA. PB and SF from 25 JIA patients were evaluated: sera from peripheral blood (white columns) and SF (black columns) were obtained and CHI3L1 amounts evaluated by ELISA (a). Columns represent mean values (±SE). *p ≤ 0.05. MNC cells obtained from SF were characterized by flow cytometry and correlation between CHI3L1 levels in SF and frequency of CD4+CD161+IL17+ cells (b), CD4+CD161+IFNγ+ cells (c) and CD4+CD161−IFNγ+ cells (d), in SF, was represented. e Correlation between CHI3L1 levels in SF and CRP serum levels in the same group of patients. f The indicated cytokines were assessed in the sera (white columns) and SF (black columns) from 25 JIA patients. Columns represent the mean values (±SE). *p ≤ 0.05. g Correlation between CHI3L1 levels in SF and IL6 (left panel) or p40 (right panel) SF levels in the same group of patients, was represented

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Clinical and Molecular Allergy

ISSN: 1476-7961

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