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Fig. 2 | Clinical and Molecular Allergy

Fig. 2

From: Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients

Fig. 2

CHI3L1 protein is secreted by Th17 and non-classic Th1 cells. a CHI3L1 protein (40 kDa) expression was evaluated on cell lysates of Th17, non classic-Th1 and classic-Th1 clones by western blot analysis. b Secreted CHI3L1 was measured on cell culture supernatants of Th17 (n = 7), non classic Th1 (n = 7) and classic Th1 (n = 7) clones after 72 h stimulation with medium (white columns), anti-CD3/CD28 mAbs (grey columns) or PMA plus Ionomycin (black columns) by ELISA. Columns represent mean values (±SE). *p ≤ 0.05

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