Table 6 Major food allergens and components available for molecular diagnostics using ImmunoCAP (or ImmunoCAP ISAC)
From: Guidelines for the use and interpretation of diagnostic methods in adult food allergy
Allergens (or allergen source) | Protein family |
|---|---|
Cupin superfamily | |
Vicilins | Ara h 1 (peanut) |
Legumins | Ara h 3 (peanut), Cor 9 (hazelnut) |
Prolamin superfamily | |
2S albumin | Ber e 1 (brazil nut), Ara h 2 (peanut), Gly m 6 |
Lipid transfer protein (LTP) | Pru p 3 (peach), Cor 8 (hazelnut), Art v 3 (Composite) Jug r 3 (walnut) |
Cereal prolamines | Tri 19 (wheat) Tri a 14 |
Pathogenesis-related (PR) proteins | |
PR10: intracellular proteins | Pru p 1 (peach), Api g 1 (celery), Gly m 4 (soy) |
PR3: chitinase Class 1 | Hev b 11, Hev b 2.6 (latex, banana, avocado) |
Profilins | Pru p 4 (peach) (Bet v 2, Phl p 12, Hev b 8) |
Cross-reactive carbohydrate determinants | MUXF3 (celery, tomato) |
Tropomyosins | Pen a 1 (shrimp) |
Calcium binding proteins | |
Parvalbumin | Gad c 1 (codfish) |
Milk proteins | Bos d 4 (α-albumin), Bos d 5 (β-lactoglobulin), Bos d 8 (casein), Bos d lactoferrin (lactoferrin) |
Egg protein | Gal d 1 (ovomucoide) |
Gal d 2 (ovalbumin) | |
Gal d 3 (conalbumin) | |
Gal d 4 (lysozyme) | |