From: Rituximab in refractory sarcoidosis: a single centre experience
References | Main organ involvement | Dose | Outcome |
---|---|---|---|
Gottenberg et al. [17] | Lymph nodes | 4Â Ă—Â 375Â mg/m2 | Good |
Belkhou et al. [15] | Lymph nodes | 2Â Ă—Â 1Â g, every 2Â weeks | Good |
Dasilva et al. [13] | Lymph nodes, including peritoneal | Two infusions, dose not specified | Good |
Bomprezzi et al. [11] | CNS and skin | 2Â Ă—Â 1Â g, every 2Â weeks, then 1Â g every 6Â months for 2Â years | Good |
Lower et al. [14] | Eye; 2 of 4 patients also had significant lung involvement | 2Â Ă—Â 1Â g, every 2Â weeks, then 375Â mg/m2 every 4 or 8Â weeks for a minimum of 24Â months or 1Â g every 4Â weeks for 10Â months | Three responders of four patients |
Sawaya et al. [12] | Neuromyelitis optica and lymph nodes | Single 1Â g infusion | Good |
Sweiss et al. [16] | Lung | 2Â Ă—Â 1Â g, every 2Â weeks | Seven full or partial responders of ten patients |