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Figure 2 | Clinical and Molecular Allergy

Figure 2

From: The clinical implications of adult-onset henoch-schonelin purpura

Figure 2

Examination revealed edema and a vesiculobullous rash in both hands and feet that showed varied degrees of healing (Figure 2A and B). Skin biopsy revealed the presence of a perivascular inflammatory infiltrate in the superficial dermal blood vessels, with nuclear dust and focal fibrinoid necrosis, consistent with leukocytoclastic vasculitis (Figure 2C; Hematoxylin and eosin stain-40x objective), accompanied by the deposition of IgA on vascular walls detected by direct immunofluorescent staining. Renal biopsy revealed focal segmental endocapillary proliferation (Figure 2D; Periodic acid- Schiff stain-40x objective) with positive immunofluorescence testing for mesangial IgA (Figure 2E; Immunoflurescence stain-40x objective)

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