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Table 2 Normal reference values for lymphocyte subsets in healthy adults determined by flow cytometry

From: Relevance of laboratory testing for the diagnosis of primary immunodeficiencies: a review of case-based examples of selected immunodeficiencies

Lymphocyte subset

95% reference values

 

18-55 years

>55 years

CD45

0.99 - 3.15 thousand/uL

1.00 - 3.33 thousand/uL

CD3

677-2383 cells/μl

617-2254 cells/μl

CD4

424-1509 cells/μl

430-1513 cells/μl

CD8

169-955 cells/μl

101-839 cells/μl

CD19

99-527 cells/μl

31-409 cells/μl

CD16+56+

101-678 cells/μl

110-657 cells/μl

CD3

59-83%

49-87%

CD4

31-59%

32-67%

CD8

12-38%

8-40%

CD19

6-22%

3-20%

CD16+56+

6-27%

6-35%

  1. Data derived from 207 healthy adult male and female donors. Pediatric reference ranges for T, B and NK cells [147].