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Table 4 MPO release from neutrophils spontaneously and after C3b-stimulation (at 0 and 20 min) in allergic rhinitis and allergic asthma during pollen season and after nasal and bronchial challenge.

From: Patients with allergic rhinitis and allergic asthma share the same pattern of eosinophil and neutrophil degranulation after allergen challenge

  Spontaneous degranulation of MPO* p-value Stimulated degranulation of MPO* p-value
  (median, range) increase 0-20 min (median, range) increase 0-20 min
  0 min 20 min   0 min 20 min  
Pollen season       
Allergic rhinitis 2.12 2.45 0.81 2.84 15.9 0.008
  (1.18 - 6.86) (1.67 - 5.64)   (0.93 - 7.07) (10.6 - 29.2)  
Allergic asthma 2.25 2.50 0.74 3.05 17.6 0.018
  (0.28 - 5.05) (0.95 - 5.5)   (0.37 - 5.20) (7.48 - 24.0)  
Nasal challenge       
Allergic rhinitis 2.61 3.16 0.68 2.93 14.9 0.043
  (1.42 - 5.64) (1.68 - 4.1)   (1.63 - 5.55) (12.7 - 21.7)  
Allergic asthma 2.21 3.31 0.018 2.35 18.4 0.018
  (1.18 - 5.62) (2.08 - 7.40)   (1.35 - 5.22) (12.6 - 25.4)  
Bronchial challenge       
Allergic rhinitis 2.42 3.43 0.075 3.88 21.6 0.028
  (2.17 - 2.92) (2.24 - 4.93)   (2.14 - 6.00) (16.8 - 27.3)  
Allergic asthma 1.50 1.91 0.018 1.58 16.8 0.018
  (0.84 - 2.3) (1.36 - 2.48)   (0.71 - 2.96) (13.1 - 23.3)  
  1. *release of MPO in % of total cell content