Table 2 ECP release from eosinophils spontaneously and after C3b-stimulation (at 0 and 20 min) in allergic rhinitis, allergic asthma and the control group during pollen season and after nasal and bronchial challenge.
Spontaneous degranulation of ECP* | p-value | Stimulated degranulation of ECP* | p-value | |||
|---|---|---|---|---|---|---|
(median, range) | increase 0-20 min | (median, range) | increase 0-20 min | |||
0 min | 20 min | 0 min | 20 min | |||
Pollen season | ||||||
Allergic rhinitis | 1.78 | 2.04 | 0.12 | 2.42 | 17.9 | 0.01 |
(0.24 - 2.88) | (0.38 - 3.17) | (0.66 - 3.79) | (9.21 - 28.6) | |||
Allergic asthma | 1.48 | 1.70 | 0.40 | 2.05 | 14.0 | 0.02 |
(0.99 - 7.10) | (0.8 - 7.32) | (0.76 - 8.97) | (7.13 - 45.1) | |||
Nasal challenge | ||||||
Allergic rhinitis | 1.23 | 2.02 | 0.04 | 1.24 | 19.5 | 0.04 |
(0.17 - 2.03) | (0.78 - 2.46) | (0.31 - 2.7) | (14.7 - 23.5) | |||
Allergic asthma | 1.78 | 2.12 | 0.02 | 1.72 | 14.9 | 0.02 |
(0.97 - 3.07) | (1.14 - 3.92) | (0.88 - 2.49) | (8.06 - 26.8) | |||
Bronchial challenge | ||||||
Allergic rhinitis | 1.50 | 2.08 | 0.12 | 2.45 | 19.8 | 0.03 |
(0.99 - 2.38) | (1.36 - 3.16) | (1.08 - 3.21) | (15.5 - 24.3) | |||
Allergic asthma | 1.66 | 1.68 | 0.4 | 1.38 | 13.2 | 0.02 |
(0.12 - 1.92) | (0.6 - 2.11) | (0.08 - 2.02) | (9.70 - 17.1) | |||