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Table 2 ECP release from eosinophils spontaneously and after C3b-stimulation (at 0 and 20 min) in allergic rhinitis, allergic asthma and the control group during pollen season and after nasal and bronchial challenge.

From: Patients with allergic rhinitis and allergic asthma share the same pattern of eosinophil and neutrophil degranulation after allergen challenge

  Spontaneous degranulation of ECP* p-value Stimulated degranulation of ECP* p-value
  (median, range) increase 0-20 min (median, range) increase 0-20 min
  0 min 20 min   0 min 20 min  
Pollen season       
Allergic rhinitis 1.78 2.04 0.12 2.42 17.9 0.01
  (0.24 - 2.88) (0.38 - 3.17)   (0.66 - 3.79) (9.21 - 28.6)  
Allergic asthma 1.48 1.70 0.40 2.05 14.0 0.02
  (0.99 - 7.10) (0.8 - 7.32)   (0.76 - 8.97) (7.13 - 45.1)  
Nasal challenge       
Allergic rhinitis 1.23 2.02 0.04 1.24 19.5 0.04
  (0.17 - 2.03) (0.78 - 2.46)   (0.31 - 2.7) (14.7 - 23.5)  
Allergic asthma 1.78 2.12 0.02 1.72 14.9 0.02
  (0.97 - 3.07) (1.14 - 3.92)   (0.88 - 2.49) (8.06 - 26.8)  
Bronchial challenge       
Allergic rhinitis 1.50 2.08 0.12 2.45 19.8 0.03
  (0.99 - 2.38) (1.36 - 3.16)   (1.08 - 3.21) (15.5 - 24.3)  
Allergic asthma 1.66 1.68 0.4 1.38 13.2 0.02
  (0.12 - 1.92) (0.6 - 2.11)   (0.08 - 2.02) (9.70 - 17.1)  
  1. * Release of ECP in % of total cell content