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Table 5 Infectious Consequences of CGD

From: Chronic granulomatous disease: a review of the infectious and inflammatory complications

Type Organ System Manifestations Etiology Diagnosis
Infectious     
  Blood stream Sepsis B Cepacia Pseudomonas Serratia Staphylococcus Salmonella Blood cultures Echocardiogram
  Pulmonary Pneumonia Aspergillus Nocardia Serratia Pseudomonas Staphylococcus Klebsiella Candida Others Radiolology Cultures Biopsy
  Cutaneous Impetigo Abscess Staphylococcus Klebsiella Aspergillus/Candida Serratia Aspirate cultures Biopsy
  Lymph node Adenitis Adenopathy Candida/Nocardia Aspergillus Serratia/Klebsiella Fine needle aspirate Cultures Biopsy
  Liver Abscess Staphylococcus Streptococcus Aspergillus/Nocardia Serratia Ultrasound or CT Aspirate Biopsy
  Bone Osteomyelitis Serratia, Aspegillus Staphylococcus Pseudomonas/Nocardia Bone scan CT/Biopsy
  GI Tract Perirectal abscess Fistulae Enterobacteriaceae Staphylococcus Biopsy Cultures
  Urinary Pyelonephritis Enterobacteriaceae Cultures IVP/CT etc
  CNS Meningitis Brain abscess Candida, Haemophilus Aspergillus Staphylococcus LP, cultures CT/MRI Biopsy
  1. CT = computerized tomography; MRI = magnetic resonance imaging; LP = lumbar puncture; IVP = intravenous pyelogram; CNS = central nervous system; GI = gastrointestinal