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Table 2 Innate and Adaptive Immunity

From: Chronic granulomatous disease: a review of the infectious and inflammatory complications

Feature

Innate

Adaptive

Action Time

Early (hours)

Late (days)

Cells

Macrophage, DC, PMN, NK cells

B and T cells

Receptors

TLR: Fixed in genome

Gene rearrangement BCRA, TCR

Recognition

Conserved molecules/PAMP

Wide Variety

Evolution

Conserved

Only vertebrates

  1. TLR = toll-like receptors; BCRA = B cell receptor for antigen; DC = dendritic cells
  2. PMN = polymorphonuclear leukocytes; B = B lymphocyte; T = T lymphocyte; TCR = T cell receptor for antigen; PAMP = pathogen-associated molecular patterns; NK cells = natural killer cells