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Table 4 Association between TSLP SNP rs1837253 minor allele T* and allergic rhinitis in Costa Rica, CAMP, and BAMSE

From: Thymic stromal lymphopoietin (TSLP) is associated with allergic rhinitis in children with asthma

 

Costa Rica

CAMP

BAMSE

Combined

Subjects

T:U

OR

P value

T:U

OR

P value

OR

P value

Fisher's P value

All children

104:122

0.85

0.18

50:81

0.62

0.003

0.72

0.089

0.003

Boys

59:93

0.63

0.004

32:55

0.58

0.007

0.56

0.04

1.2 × 10-4

Girls^

45:29

1.55

0.08

18:26

0.69

0.11

1.02

0.48

 
  1. *Allele frequency 0.24 in Costa Rica, 0.21 in CAMP, 0.27 in BAMSE
  2. T:U = ratio of transmitted to untransmitted alleles
  3. ^Fisher's combined P value not calculated because direction of effect inconsistent across females in these cohort.