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Table 1 Identification of offspring based on FcRn genotype and history of exposure to the effects of maternal allergy.

From: IgG transmitted from allergic mothers decreases allergic sensitization in breastfed offspring

Offspring mice (FcRn genotype/Nursing mother)

Prenatal Exposure (Pregnancy)

Postnatal Exposure (Nursing)

FcRn+/- /B6naive#

B6naive

B6naive

FcRn-/- /B6AAD

B6naive

*B6AAD

FcRn+/- /B6AAD

B6naive

*B6AAD

FcRn+/+ /B6AAD##

B6AAD

B6AAD

  1. * Offspring born to naïve females were adoptively nursed by B6AAD mothers.
  2. # Positive control for disease, ## positive control for protection.