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Table 3 HLA-DR and HLA-DQ allele frequencies in children with Alternaria -sensitive moderate-severe asthma compared to Alternaria -sensitive mild asthma.

From: Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma

Study

Moderate-Severe

(60)

Mild

(49)

P

HLA-DRB1

   

*01

10 (0.051)

8 (0.041)

 

*03

29 (0.153)

20 (0.102)

 

*04

14 (0.076)

29 (0.153)

 

*07

24 (0.127)

27 (0.143)

 

*08

7 (0.034)

10 (0.061)

 

*09

7 (0.034)

4 (0.020)

 

*10

2 (0.008)

2 (0.010)

 

*11

17 (0.093)

33 (0.184)

 

*12

7 (0.034)

2 (0.010)

 

*13

37 (0.195)

20 (0.112)

0.06

*14

3 (0.017)

2 (0.010)

 

*15

27 (0.161)

27 (0.143)

 

*16

3 (0.010)

2 (0.010)

 

HLA-DQB1

   

*02

42 (0.254)

33 (0184)

 

*03

39 (0.220)

63 (0.398)

0.02 (0.007)

*04

12 (0.068)

8 (0.041)

 

*05

31 (0.161)

20 (0.102)

 

*06

44 (0.288)

51 (0.276)

 
  1. Data presented as percentage of patients with allele and in parentheses allele frequency.
  2. P value using Fisher's exact test.